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Cellosaurus HuCC-A1 (CVCL_M255)

[Text version]
Cell line name HuCC-A1
Synonyms HuCCA-1; HuCCA1
Accession CVCL_M255
Resource Identification Initiative To cite this cell line use: HuCC-A1 (RRID:CVCL_M255)
Comments Population: Southeast Asian; Thai.
Doubling time: ~55 hours (PubMed=1666951).
Omics: Proteomics; Subcellular; Secretome.
Derived from site: In situ; Bile duct; UBERON=UBERON_0002394.
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Opisthorchis viverrini-related cholangiocarcinoma (NCIt: C27769)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_HF36 (HuCC-A1Nu)
Sex of cell Male
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1657

Markers:
AmelogeninX
CSF1PO10,11
D5S81812
D7S82010,11
D13S3178
D16S53911,12
TH019
TPOX9
vWA14,19

Run an STR similarity search on this cell line
Web pages Info; -; -; https://www2.cri.or.th/lab/biochemistry/res_act
Publications

PubMed=1666951
Stitaya Sirisinha, Tasanee Tengchaisri, Somnate Boonpucknavig, Nalinee Prempracha, Samrerng Ratanarapee, Arun Pausawasdi;
Establishment and characterization of a cholangiocarcinoma cell line from a Thai patient with intrahepatic bile duct cancer.
Asian Pac. J. Allergy Immunol. 9:153-157(1991)

PubMed=9031402
Siriporn Sriurairatana, Tasanee Tengchaisri, Stitaya Sirisinha;
Ultrastructural characteristics of liver fluke associated human cholangiocarcinoma cell lines.
Southeast Asian J. Trop. Med. Public Health 27:57-62(1996)

PubMed=12587840
Tasanee Panichakul, Thiwaree Wanun, Vichai Reutrakul, Stitaya Sirisinha;
Synergistic cytotoxicity and apoptosis induced in human cholangiocarcinoma cell lines by a combined treatment with tumor necrosis factor-alpha (TNF-alpha) and triptolide.
Asian Pac. J. Allergy Immunol. 20:167-173(2002)

PubMed=15048994; DOI=10.1002/pmic.200300651
Chantragan Srisomsap, Phannee Sawangareetrakul, Pantipa Subhasitanont, Tasanee Panichakul, Siriporn Keeratichamroen, Kriengsak Lirdprapamongkol, Daranee Chokchaichamnankit, Stitaya Sirisinha, Jisnuson Svasti;
Proteomic analysis of cholangiocarcinoma cell line.
Proteomics 4:1135-1144(2004)

PubMed=16475706
Tasanee Panichakul, Pakamas Intachote, Adisak Wongkajornsilp, Banchob Sripa, Stitaya Sirisinha;
Triptolide sensitizes resistant cholangiocarcinoma cells to TRAIL-induced apoptosis.
Anticancer Res. 26:259-265(2006)

PubMed=20069059; DOI=10.1155/2010/437143; PMCID=PMC2801507
Chantragan Srisomsap, Phannee Sawangareetrakul, Pantipa Subhasitanont, Daranee Chokchaichamnankit, Khajeelak Chiablaem, Vajarabhongsa Bhudhisawasdi, Sopit Wongkham, Jisnuson Svasti;
Proteomic studies of cholangiocarcinoma and hepatocellular carcinoma cell secretomes.
J. Biomed. Biotechnol. 2010:437143.1-437143.18(2010)

CLPUB00275
Sebastian Zach, Emrullah Birgin, Felix Ruckert;
Primary cholangiocellular carcinoma cell lines.
J. Stem Cell Res. Transplant. 2:1013-1013(2015)

PubMed=31077409; DOI=10.1002/hep.30704
Gunya Sittithumcharee, Orawan Suppramote, Kulthida Vaeteewoottacharn, Chumphon Sirisuksakun, Supawan Jamnongsong, Phatthamon Laphanuwat, Monthira Suntiparpluacha, Arriya Matha, Porncheera Chusorn, Pongsakorn Buraphat, Chumpot Kakanaporn ...Show all 21 authors... , Komgrid Charngkaew, Atit Silsirivanit, Krittiya Korphaisarn, Somchai Limsrichamrern, Pinpat Tripatara, Chawalit Pairojkul, Sopit Wongkham, Somponnat Sampattavanich, Seiji Okada, Siwanon Jirawatnotai; Show fewer authors
Dependency of cholangiocarcinoma on cyclin D-dependent kinase activity.
Hepatology 70:1614-1630(2019)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155
Abdulkadir Isidan, Ali Yenigun, Daiki Soma, Eric Aksu, Kevin Lopez, Yujin Park, Arthur Cross-Najafi, Ping Li, Debjyoti Kundu, Michael G. House, Sanjukta Chakraborty ...Show all 17 authors... , Shannon Glaser, Lindsey Kennedy, Heather Francis, Wen-Jun Zhang, Gianfranco D. Alpini, Burcin Ekser; Show fewer authors
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

Cross-references
Cell line collections (Providers) JCRB; JCRB1657
Chemistry resources ChEMBL-Cells; CHEMBL4513113
ChEMBL-Targets; CHEMBL4513129
PubChem_Cell_line; CVCL_M255
Encyclopedic resources Wikidata; Q54896723
Entry history
Entry creation05-Nov-2013
Last entry update10-Apr-2025
Version number20