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Cellosaurus HepDE19 (CVCL_M178)

[Text version]
Cell line name HepDE19
Synonyms DE19
Accession CVCL_M178
Resource Identification Initiative To cite this cell line use: HepDE19 (RRID:CVCL_M178)
Comments Population: Caucasian.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=17804499; DOI=10.1128/JVI.01123-07; PMCID=PMC2169032
Hai-Tao Guo, Dong Jiang, Tian-Lun Zhou, Andrea Cuconati, Timothy M. Block, Ju-Tao Guo;
Characterization of the intracellular deproteinized relaxed circular DNA of hepatitis B virus: an intermediate of covalently closed circular DNA formation.
J. Virol. 81:12472-12484(2007)

PubMed=17875990; DOI=10.1128/AAC.00541-07; PMCID=PMC2167973
Anne Marie Dougherty, Hai-Tao Guo, Gael Westby, Yuan-Jie Liu, Ender Simsek, Ju-Tao Guo, Anand Mehta, Pamela Norton, Bao-Hua Gu, Timothy M. Block, Andrea Cuconati;
A substituted tetrahydro-tetrazolo-pyrimidine is a specific and novel inhibitor of hepatitis B virus surface antigen secretion.
Antimicrob. Agents Chemother. 51:4427-4437(2007)

Cross-references
Cell line databases/resources cancercelllines; CVCL_M178
Encyclopedic resources Wikidata; Q54882838
Entry history
Entry creation06-May-2013
Last entry update19-Dec-2024
Version number18