Cellosaurus logo
expasy logo

Cellosaurus COG-LL-317 (CVCL_M159)

[Text version]
Cell line name COG-LL-317
Accession CVCL_M159
Resource Identification Initiative To cite this cell line use: COG-LL-317 (RRID:CVCL_M159)
Comments Part of: NCI Pediatric Preclinical Testing Program (PPTP) cell line panel.
Doubling time: 21 hours (PubMed=20922763); 30-40 hours (COG).
Karyotypic information: 46,XY,t(8;14)(q24.1;q11.2) (COG).
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: T-cell; CL=CL_0000084.
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_M160 ! COG-LL-317h
Sex of cell Male
Age at sampling 1Y7M
Category Cancer cell line
STR profile Source(s): COG; PubMed=20922763

Markers:
AmelogeninX,Y
CSF1PO10
D2S133817,18
D3S135816,17
D5S81811,13
D7S82011,13
D8S117915
D13S3178,12
D16S5399,11
D18S5114,18
D19S43314,16
D21S1130
FGA20,23
TH017,8
TPOX8,11
vWA16,17

Run an STR similarity search on this cell line
Web pages Provider; CCR; -; https://www.cccells.org/PDF_Files/LL-PDX/COG-LL-317.pdf
Provider; CCR; -; https://www.cccells.org/suppdata/dl/3karyotypes_2007-02-09.pdf
Publications

PubMed=19298590; DOI=10.1111/j.1365-2141.2009.07631.x
Min H. Kang, Narine Harutyunyan, Connor P. Hall, Rachael A. Papa, Richard B. Lock;
Methotrexate and aminopterin exhibit similar in vitro and in vivo preclinical activity against acute lymphoblastic leukaemia and lymphoma.
Br. J. Haematol. 145:389-393(2009)

PubMed=20922763; DOI=10.1002/pbc.22801; PMCID=PMC3005554
Min H. Kang, Malcolm A. Smith, Christopher L. Morton, Nino Keshelava, Peter J. Houghton, Charles Patrick Reynolds;
National Cancer Institute pediatric preclinical testing program: model description for in vitro cytotoxicity testing.
Pediatr. Blood Cancer 56:239-249(2011)

PubMed=35354797; DOI=10.1038/s41467-022-29224-5; PMCID=PMC8967900
Isabelle Rose Leo, Luay Aswad, Matthias Stahl, Elena Kunold, Frederik Post, Tom Erkers, Nona Struyf, Georgios Mermelekas, Rubin Narayan Joshi, Eva Gracia-Villacampa, Paivi Ostling ...Show all 17 authors... , Olli-Pekka Kallioniemi, Katja Pokrovskaja Tamm, Ioannis Siavelis, Janne Lehtio, Mattias Vesterlund, Rozbeh Jafari; Show fewer authors
Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines.
Nat. Commun. 13:1691.1-1691.19(2022)

Cross-references
Encyclopedic resources Wikidata; Q54813969
Gene expression databases GEO; GSM5137710
Proteomic databases PRIDE; PXD023662
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number17