Cellosaurus cell line TsuGK27 (CVCL

Cross-references
Cell line name	TsuGK27
Synonyms	TSUGK27; TSUGK-27
Accession	CVCL_M134
Resource Identification Initiative	To cite this cell line use: TsuGK27 (RRID:CVCL_M134)
Comments	Problematic cell line: Contaminated. Parent cell line (TSU-Pr1) has been shown to be a T24 derivative. Population: Caucasian; Swedish. Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations	Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease	Bladder carcinoma (NCIt: C4912)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_4014 (TSU-Pr1)
Sex of cell	Female
Age at sampling	82Y
Category	Cancer cell line
Publications	PubMed=9365544; DOI=10.1002/(SICI)1097-0045(19971101)33:3<166::AID-PROS4>3.0.CO;2-H Jurgen Erich Gschwend, William R. Fair, C. Thomas Powell; Evaluation of the tetracycline-repressible transactivator system for inducible gene expression in human prostate cancer cell lines. Prostate 33:166-176(1997)
Cell line databases/resources	cancercelllines; CVCL_M134
Encyclopedic resources	Wikidata; Q54973175
Entry history
Entry creation	06-May-2013
Last entry update	19-Dec-2024
Version number	16