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Cellosaurus KCP-4 (CVCL_M123)

[Text version]
Cell line name KCP-4
Accession CVCL_M123
Resource Identification Initiative To cite this cell line use: KCP-4 (RRID:CVCL_M123)
Comments Problematic cell line: Contaminated. Grand-parent cell line (KB) has been shown to be a HeLa derivative.
Population: African American.
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2088 (KB-3-1)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line

PubMed=8200854; DOI=10.1111/j.1349-7006.1994.tb02376.x
Fujii R.-i., Mutoh M., Niwa K., Yamada K., Aikou T., Nakagawa M., Kuwano M., Akiyama S.-i.
Active efflux system for cisplatin in cisplatin-resistant human KB cells.
Jpn. J. Cancer Res. 85:426-433(1994)

PubMed=22562377; DOI=10.3892/or.2012.1801
Oiso S., Ikeda R., Nakamura K., Takeda Y., Akiyama S.-i., Kariyazono H.
Involvement of NF-kappaB activation in the cisplatin resistance of human epidermoid carcinoma KCP-4 cells.
Oncol. Rep. 28:27-32(2012)

PubMed=24317338; DOI=10.3892/or.2013.2896
Oiso S., Takayama Y., Nakazaki R., Matsunaga N., Motooka C., Yamamura A., Ikeda R., Nakamura K., Takeda Y., Kariyazono H.
Factors involved in the cisplatin resistance of KCP-4 human epidermoid carcinoma cells.
Oncol. Rep. 31:719-726(2014)

Encyclopedic resources Wikidata; Q54899700
Entry history
Entry creation06-May-2013
Last entry update05-Oct-2023
Version number15