ID   KCP-4
AC   CVCL_M123
DR   Wikidata; Q54899700
RX   PubMed=8200854;
RX   PubMed=22562377;
RX   PubMed=24317338;
CC   Problematic cell line: Contaminated. Grand-parent cell line (KB) has been shown to be a HeLa derivative.
CC   Population: African American.
CC   Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2088 ! KB-3-1
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 06-05-13; Last updated: 05-10-23; Version: 15
//
RX   PubMed=8200854; DOI=10.1111/j.1349-7006.1994.tb02376.x;
RA   Fujii R.-i., Mutoh M., Niwa K., Yamada K., Aikou T., Nakagawa M.,
RA   Kuwano M., Akiyama S.-i.;
RT   "Active efflux system for cisplatin in cisplatin-resistant human KB
RT   cells.";
RL   Jpn. J. Cancer Res. 85:426-433(1994).
//
RX   PubMed=22562377; DOI=10.3892/or.2012.1801;
RA   Oiso S., Ikeda R., Nakamura K., Takeda Y., Akiyama S.-i.,
RA   Kariyazono H.;
RT   "Involvement of NF-kappaB activation in the cisplatin resistance of
RT   human epidermoid carcinoma KCP-4 cells.";
RL   Oncol. Rep. 28:27-32(2012).
//
RX   PubMed=24317338; DOI=10.3892/or.2013.2896;
RA   Oiso S., Takayama Y., Nakazaki R., Matsunaga N., Motooka C.,
RA   Yamamura A., Ikeda R., Nakamura K., Takeda Y., Kariyazono H.;
RT   "Factors involved in the cisplatin resistance of KCP-4 human epidermoid
RT   carcinoma cells.";
RL   Oncol. Rep. 31:719-726(2014).
//