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Cellosaurus UROtsa Cd#1-SPARC (CVCL_LM65)

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Cell line name UROtsa Cd#1-SPARC
Synonyms Cd#1-SPARC
Accession CVCL_LM65
Resource Identification Initiative To cite this cell line use: UROtsa Cd#1-SPARC (RRID:CVCL_LM65)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11219; SPARC.
Transformant: ChEBI; CHEBI_48775; Cadmium(2+).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Urinary bladder, urothelium; UBERON=UBERON_0004645.
Cell type: Urothelial cell; CL=CL_0000731.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_IX03 (UROtsa Cd#1)
Sex of cell Female
Age at sampling 12Y
Category Transformed cell line
Publications

PubMed=26783756; DOI=10.1371/journal.pone.0147362; PMCID=PMC4718619
Andrea Slusser-Nore, Jennifer L. Larson-Casey, Ruo-Wen Zhang, Xu-Dong Zhou, Seema Somji, Scott H. Garrett, Donald A. Sens, Jane R. Dunlevy;
SPARC expression is selectively suppressed in tumor initiating urospheres isolated from As+3- and Cd+2-transformed human urothelial cells (UROtsa) stably transfected with SPARC.
PLoS ONE 11:e0147362.1-e0147362.22(2016)

Cross-references
Encyclopedic resources Wikidata; Q54991828
Entry history
Entry creation15-Nov-2017
Last entry update10-Apr-2025
Version number9