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Cellosaurus PLC/PRF/5 Luciferase/GFP (CVCL_LJ87)

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Cell line name PLC/PRF/5 Luciferase/GFP
Synonyms Luciferase/GFP dual-labeled PLC/PRF/5; PLC/PRF/5 dual-labeled
Accession CVCL_LJ87
Resource Identification Initiative To cite this cell line use: PLC/PRF/5 Luciferase/GFP (RRID:CVCL_LJ87)
Comments Population: African; Shangaan.
Karyotypic information: Has lost chromosome Y (from parent cell line).
Transfected with: UniProtKB; P08659; Firefly luciferase.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg112Gly (c.334C>G) (p.Pro126Arg, c.377C>G); ClinVar=VCV000233484; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg249Ser (c.747G>T); ClinVar=VCV000012352; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 12363; TSC2; Simple; p.Asn1651Ser (c.4952A>G); ClinVar=VCV000049335; Zygosity=Homozygous (from parent cell line).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0485 (PLC/PRF/5)
Sex of cell Male
Age at sampling 24Y
Category Cancer cell line
Web pages http://www.genecopoeia.com/wp-content/uploads/oldpdfs/product/Luciferase-GFP/datasheet_SCL-C09-HLG.pdf
Cell line databases/resources cancercelllines; CVCL_LJ87
Encyclopedic resources Wikidata; Q54947575
Entry history
Entry creation15-Nov-2017
Last entry update05-Oct-2023
Version number11