Cellosaurus logo
expasy logo

Cellosaurus LM-NSC008 (CVCL_LJ42)

[Text][XML][JSON]
Cell line name LM-NSC008
Synonyms LM008; L-MYC-Neural Stem Cell 008
Accession CVCL_LJ42
Resource Identification Initiative To cite this cell line use: LM-NSC008 (RRID:CVCL_LJ42)
Comments Doubling time: ~30 hours (PubMed=27546534).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7555; MYCL.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Omics: Variations; CNV analysis.
Derived from site: In situ; Fetal brain; UBERON=UBERON_0006238.
Cell type: Neural stem cell; CL=CL_0000047.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 10-14FW
Category Somatic stem cell
Publications

PubMed=27546534; DOI=10.1016/j.stemcr.2016.07.013; PMCID=PMC5031988
Zhong-Qi Li, Diana Oganesyan, Rachael Mooney, Xian-Fang Rong, Matthew J. Christensen, David Shahmanyan, Patrick Mcdevitt Perrigue, Joseph Benetatos, Lusine Tsaturyan, Soraya Aramburo, Alexandra Jacqueline Annala ...Show all 18 authors... , Yang Lu, Joseph Najbauer, Xi-Wei Wu, Michael Edward Barish, David Lozoff Brody, Karen S. Aboody, Margarita Gutova; Show fewer authors
L-MYC expression maintains self-renewal and prolongs multipotency of primary human neural stem cells.
Stem Cell Reports 7:483-495(2016)

PubMed=30071048; DOI=10.1371/journal.pone.0199967; PMCID=PMC6071994
Russell C. Rockne, Vikram Adhikarla, Lusine Tsaturyan, Zhong-Qi Li, Meher B. Masihi, Karen S. Aboody, Michael Edward Barish, Margarita Gutova;
Long-term stability and computational analysis of migration patterns of L-MYC immortalized neural stem cells in the brain.
PLoS ONE 13:e0199967.1-e0199967.15(2018)

Cross-references
Cell line collections (Providers) ABM; T0682 - Discontinued
Kerafast; ECH002 - Discontinued
Encyclopedic resources Wikidata; Q54902722
Gene expression databases GEO; GSM2228431
GEO; GSM2228432
GEO; GSM2228435
Entry history
Entry creation15-Nov-2017
Last entry update14-Aug-2025
Version number15