ID   LM-NSC008
AC   CVCL_LJ42
SY   LM008; L-MYC-Neural Stem Cell 008
DR   ABM; T0682
DR   GEO; GSM2228431
DR   GEO; GSM2228432
DR   GEO; GSM2228435
DR   Kerafast; ECH002
DR   Wikidata; Q54902722
RX   PubMed=27546534;
RX   PubMed=30071048;
CC   Doubling time: ~30 hours (PubMed=27546534).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7555; MYCL.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; CNV analysis.
CC   Discontinued: ABM; T0682; true.
CC   Discontinued: Kerafast; ECH002; true.
CC   Derived from site: In situ; Fetal brain; UBERON=UBERON_0006238.
CC   Cell type: Neural stem cell; CL=CL_0000047.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   10-14FW
CA   Somatic stem cell
DT   Created: 15-11-17; Last updated: 10-04-25; Version: 14
//
RX   PubMed=27546534; DOI=10.1016/j.stemcr.2016.07.013; PMCID=PMC5031988;
RA   Li Z.-Q., Oganesyan D., Mooney R., Rong X.-F., Christensen M.J.,
RA   Shahmanyan D., Perrigue P.M., Benetatos J., Tsaturyan L., Aramburo S.,
RA   Annala A.J., Lu Y., Najbauer J., Wu X.-W., Barish M.E., Brody D.L.,
RA   Aboody K.S., Gutova M.;
RT   "L-MYC expression maintains self-renewal and prolongs multipotency of
RT   primary human neural stem cells.";
RL   Stem Cell Reports 7:483-495(2016).
//
RX   PubMed=30071048; DOI=10.1371/journal.pone.0199967; PMCID=PMC6071994;
RA   Rockne R.C., Adhikarla V., Tsaturyan L., Li Z.-Q., Masihi M.B.,
RA   Aboody K.S., Barish M.E., Gutova M.;
RT   "Long-term stability and computational analysis of migration patterns
RT   of L-MYC immortalized neural stem cells in the brain.";
RL   PLoS ONE 13:e0199967.1-e0199967.15(2018).
//