| Cell line name |
HT-29/B6 |
| Synonyms |
HT29/B6 |
| Accession |
CVCL_LJ30 |
| Resource Identification Initiative |
To cite this cell line use: HT-29/B6 (RRID:CVCL_LJ30) |
| Comments |
Population: Caucasian. Characteristics: Derived from a glucose-free culture of HT-29. Derived from site: In situ; Colon; UBERON=UBERON_0001155. |
| Sequence variations |
- Mutation; HGNC; HGNC:583; APC; Simple; p.Glu853Ter (c.2557G>T); ClinVar=VCV001071632; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Pro449Thr (c.1345C>A); ClinVar=VCV001333250; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Gln311Ter (c.931C>T); ClinVar=VCV000230663; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
|
| Disease |
Colon adenocarcinoma (NCIt: C4349) |
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
| Hierarchy |
Parent: CVCL_0320 (HT-29) |
| Sex of cell |
Female |
| Age at sampling |
44Y |
| Category |
Cancer cell line |
| Publications | PubMed=1656765; DOI=10.1152/ajpcell.1991.261.4.C574 Klaus-Martin Kreusel, Michael Fromm, Jorg-Dieter Schulzke, Ulrich Hegel; Cl- secretion in epithelial monolayers of mucus-forming human colon cells (HT-29/B6). Am. J. Physiol. 261:C574-C582(1991) PubMed=11533143; DOI=10.1111/j.1469-7793.2001.00541.x; PMCID=PMC2278785 Christian Bojarski, Alfred H. Gitter, Kerstin Bendfeldt, Joachim Mankertz, Heinz Schmitz, Siegfried Wagner, Michael Fromm, Jorg-Dieter Schulzke; Permeability of human HT-29/B6 colonic epithelium as a function of apoptosis. J. Physiol. (Lond.) 535:541-552(2001) |
| Cross-references |
| Cell line databases/resources |
cancercelllines; CVCL_LJ30
|
| Encyclopedic resources |
Wikidata; Q54896526
|
| Entry history |
| Entry creation | 15-Nov-2017 |
| Last entry update | 19-Dec-2024 |
| Version number | 16 |
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