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Cellosaurus SC263 R10.2 (CVCL_LI56)

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Cell line name SC263 R10.2
Accession CVCL_LI56
Resource Identification Initiative To cite this cell line use: SC263 R10.2 (RRID:CVCL_LI56)
Comments Selected for resistance to: DrugBank; DB00002; Cetuximab (Erbitux).
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.704_735del32; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg306Ter (c.916C>T); ClinVar=VCV000142144; Zygosity=Unspecified (from parent cell line).
Disease Head and neck squamous cell carcinoma (NCIt: C34447)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_LI51 (NKI-SC263)
Category Cancer cell line
Publications

PubMed=26269754; PMCID=PMC4529614
Carolien Boeckx, Lina Blockx, Ken Op de Beeck, Ridha Limame, Guy Van Camp, Marc Peeters, Jan B. Vermorken, Pol Specenier, An Wouters, Marc Baay, Filip Lardon;
Establishment and characterization of cetuximab resistant head and neck squamous cell carcinoma cell lines: focus on the contribution of the AP-1 transcription factor.
Am. J. Cancer Res. 5:1921-1938(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_LI56
Encyclopedic resources Wikidata; Q54952247
Entry history
Entry creation15-Nov-2017
Last entry update19-Dec-2024
Version number9