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Cellosaurus VACO 432 PIK3CA (H1047R/+) (CVCL_LD57)

[Text version]
Cell line name VACO 432 PIK3CA (H1047R/+)
Synonyms PIK3CA (H1047R/+) VACO 432
Accession CVCL_LD57
Resource Identification Initiative To cite this cell line use: VACO 432 PIK3CA (H1047R/+) (RRID:CVCL_LD57)
Comments Characteristics: Heterozygous knockin of a PIK3CA kinase domain activating mutation.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple_edited; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous; Note=By method not specified (Horizon Discovery).
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5402 (VACO 432)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
Cell line collections (Providers) Horizon_Discovery; HD+107-003
Cell line databases/resources cancercelllines; CVCL_LD57
Encyclopedic resources Wikidata; Q54992738
Entry history
Entry creation22-Aug-2017
Last entry update05-Oct-2023
Version number10