Cellosaurus cell line EBC-1 KRAS (G12D/+/+/+) (CVCL

Cross-references
Cell line name	EBC-1 KRAS (G12D/+/+/+)
Synonyms	KRAS (G12D/+/+/+) EBC-1
Accession	CVCL_LC83
Resource Identification Initiative	To cite this cell line use: EBC-1 KRAS (G12D/+/+/+) (RRID:CVCL_LC83)
Comments	Population: Chinese; Taiwan. Characteristics: Heterozygous knockin of a KRAS activating mutation. Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
Sequence variations	Mutation; HGNC; HGNC:2731; DDR2; Simple; p.Thr681Ile (c.2042C>T); ClinVar=VCV001435412; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:6407; KRAS; Simple_edited; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous; Note=By method not specified (Horizon_Discovery=HD+121-001). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
Disease	Lung squamous cell carcinoma (NCIt: C3493)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_2891 (EBC-1)
Sex of cell	Male
Age at sampling	69Y
Category	Cancer cell line
Cell line collections (Providers)	Horizon_Discovery; HD+121-001
Cell line databases/resources	cancercelllines; CVCL_LC83
Encyclopedic resources	Wikidata; Q54831757
Entry history
Entry creation	22-Aug-2017
Last entry update	19-Dec-2024
Version number	15