ID   EBC-1 KRAS (G12D/+/+/+)
AC   CVCL_LC83
SY   KRAS (G12D/+/+/+) EBC-1
DR   cancercelllines; CVCL_LC83
DR   Horizon_Discovery; HD+121-001
DR   Wikidata; Q54831757
CC   Population: Chinese; Taiwan.
CC   Characteristics: Heterozygous knockin of a KRAS activating mutation.
CC   Sequence variation: Mutation; HGNC; 2731; DDR2; Simple; p.Thr681Ile (c.2042C>T); ClinVar=VCV001435412; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple_edited; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous; Note=By method not specified (Horizon_Discovery=HD+121-001).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Glu171Ter (c.511G>T); ClinVar=VCV000634771; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
DI   NCIt; C3493; Lung squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2891 ! EBC-1
SX   Male
AG   69Y
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 10-09-24; Version: 14
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