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Cellosaurus NIH-3T3-G185 (CVCL_L991)

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Cell line name NIH-3T3-G185
Synonyms NIH 3T3-G185; NIH 3T3 G185; NIH3T3-G185; NIH MDR1-G185; NIH-MDR-G185; G185
Accession CVCL_L991
Resource Identification Initiative To cite this cell line use: NIH-3T3-G185 (RRID:CVCL_L991)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:40; ABCB1.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: NIH Swiss.
Hierarchy Parent: CVCL_0594 (NIH 3T3)
Sex of cell Male
Age at sampling Embryo
Category Spontaneously immortalized cell line
Publications

PubMed=1356986; DOI=10.1016/S0021-9258(19)36791-2
Edward P. Bruggemann, Stephen J. Currier, Michael Marc Gottesman, Ira Pastan;
Characterization of the azidopine and vinblastine binding site of P-glycoprotein.
J. Biol. Chem. 267:21020-21026(1992)

PubMed=7866993
Carol O. Cardarelli, Ivan Aksentijevich, Ira Pastan, Michael Marc Gottesman;
Differential effects of P-glycoprotein inhibitors on NIH3T3 cells transfected with wild-type (G185) or mutant (V185) multidrug transporters.
Cancer Res. 55:1086-1091(1995)

Cross-references
Anatomy/cell type resources BTO; BTO_0002396
Chemistry resources ChEMBL-Cells; CHEMBL3988465
PubChem_Cell_line; CVCL_L991
Encyclopedic resources Wikidata; Q54930588
Entry history
Entry creation06-May-2013
Last entry update14-Aug-2025
Version number15