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Cellosaurus COS31 (CVCL_L346)

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Cell line name COS31
Synonyms COS 31; Canine osteosarcoma cells from passage 31
Accession CVCL_L346
Resource Identification Initiative To cite this cell line use: COS31 (RRID:CVCL_L346)
Comments Doubling time: 28 hours (PubMed=9827352).
Omics: Transcriptomics; RNAseq; Single cell.
Derived from site: Metastatic; Bone, left distal radius; UBERON=UBERON_0004407.
Disease Canine osteosarcoma (NCIt: C120045)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Saint Bernard; VBO=VBO_0201160.
Hierarchy Children:
CVCL_L347 (COS31/rCDDP)
Sex of cell Male
Age at sampling 6Y
Category Cancer cell line
Publications

PubMed=9827351
Ahmed M. Shoieb, Kevin A. Hahn, Riette L. Van Laack, Mary A. Barnhill;
In vitro reversal of glutathione-S-transferase-mediated resistance in canine osteosarcoma (COS31) cells.
In Vivo 12:455-462(1998)

PubMed=9827352
Ahmed M. Shoieb, Kevin A. Hahn, Mary A. Barnhill;
An in vivo/in vitro experimental model system for the study of human osteosarcoma: canine osteosarcoma cells (COS31) which retain osteoblastic and metastatic properties in nude mice.
In Vivo 12:463-472(1998)

PubMed=33446089; DOI=10.1177/1040638720985242; PMCID=PMC7944434
Jordan Ayers, Rowan J. Milner, Galaxia Cortes-Hinojosa, Alberto Riva, Sandra M. Axiak-Bechtel, Bikash Sahay, Matthew Cascio, Amandine Lejeune, Keijiro Shiomitsu, Carlos Souza, Oscar Hernandez, Marc E. Salute;
Novel application of single-cell next-generation sequencing for determination of intratumoral heterogeneity of canine osteosarcoma cell lines.
J. Vet. Diagn. Invest. 33:261-278(2021)

Cross-references
Anatomy/cell type resources BTO; BTO_0005363
Encyclopedic resources Wikidata; Q54814327
Entry history
Entry creation06-May-2013
Last entry update10-Apr-2025
Version number14