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Cellosaurus SNU-719-DOX (CVCL_L053)

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Cell line name SNU-719-DOX
Synonyms SNU-719R-DOX/100
Accession CVCL_L053
Resource Identification Initiative To cite this cell line use: SNU-719-DOX (RRID:CVCL_L053)
Comments Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Selected for resistance to: ChEBI; CHEBI_28748; Doxorubicin (Adriablastin; Adriamycin).
Derived from site: In situ; Stomach; UBERON=UBERON_0000945.
Sequence variations
  • Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Gly34Val (c.101G>T); ClinVar=VCV000017582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7029; MET; Simple; p.Asp153Ala (c.458A>C); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Pro104Arg (c.311C>G); ClinVar=VCV001480334; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:667; RHOA; Simple; p.Ala61Val (c.182C>T); Zygosity=Heterozygous (from parent cell line).
Disease Gastric tubular adenocarcinoma (NCIt: C5473)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5086 (SNU-719)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=14734480; DOI=10.1158/1078-0432.CCR-1025-3
Hio Chung Kang, Il-Jin Kim, Jae-Hyun Park, Yong Shin, Ja-Lok Ku, Mi Sun Jung, Byong Chul Yoo, Hark Kyun Kim, Jae-Gahb Park;
Identification of genes with differential expression in acquired drug-resistant gastric cancer cells using high-density oligonucleotide microarrays.
Clin. Cancer Res. 10:272-284(2004)

PubMed=19956504; DOI=10.4143/crt.2005.37.1.1; PMCID=PMC2785416
Ja-Lok Ku, Jae-Gahb Park;
Biology of SNU cell lines.
Cancer Res. Treat. 37:1-19(2005)

Cross-references
Cell line databases/resources cancercelllines; CVCL_L053
Encyclopedic resources Wikidata; Q54955257
Entry history
Entry creation06-May-2013
Last entry update14-Aug-2025
Version number19