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Cellosaurus RTL-W1 (CVCL_L011)

[Text version]
Cell line name RTL-W1
Synonyms Rainbow Trout Liver-Waterloo 1
Accession CVCL_L011
Resource Identification Initiative To cite this cell line use: RTL-W1 (RRID:CVCL_L011)
Comments Group: Fish cell line.
Doubling time: 98.9 hours (PubMed=29268113).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) (NCBI Taxonomy: 8022)
Sex of cell Male
Age at sampling 4Y
Category Spontaneously immortalized cell line
Publications

PubMed=8299006; DOI=10.1007/BF00755606
Lucy E.J. Lee, Janine H. Clemons, Daniel G. Bechtel, Sarah J. Caldwell, Kyu-Bo Han, Maria Pasitschniak-Arts, Dick D. Mosser, Niels C. Bols;
Development and characterization of a rainbow trout liver cell line expressing cytochrome P450-dependent monooxygenase activity.
Cell Biol. Toxicol. 9:279-294(1993)

PubMed=7766144; DOI=10.1007/BF00749903
Niels C. Bols, Rosemarie Catherine Ganassin, Denise J. Tom, Lucy E.J. Lee;
Growth of fish cell lines in glutamine-free media.
Cytotechnology 16:159-166(1994)

PubMed=11501281; DOI=10.1002/tox.1039
Sebastian Nehls, Helmut Segner;
Detection of DNA damage in two cell lines from rainbow trout, RTG-2 and RTL-W1, using the comet assay.
Environ. Toxicol. 16:321-329(2001)

PubMed=19002917; DOI=10.1023/A:1020516804173; PMCID=PMC3449788
Guy M.L. Perry, Gordon J. McDonald, Moira M. Ferguson, Rosemarie Catherine Ganassin, Niels C. Bols;
Characterization of rainbow trout cell lines using microsatellite DNA profiling.
Cytotechnology 37:143-151(2001)

DOI=10.1016/S1873-0140(05)80005-0
Niels C. Bols, Vivian R. Dayeh, Lucy E.J. Lee, Kristin Schirmer;
Use of fish cell lines in the toxicology and ecotoxicology of fish Piscine cell lines in environmental toxicology.
(In book chapter) Biochemistry and molecular biology of fishes, Vol. 6; Mommsen, Thomas P. & Moon, Thomas W. (eds.); pp.43-84; Elsevier; Amsterdam; Netherlands (2005)

PubMed=20420918; DOI=10.1016/j.fsi.2010.04.007
Atsushi Kawano, Steve C. Kales, Kazuhiro Fujiki, Stephanie J. DeWitte-Orr, Brian Dixon, Lucy E.J. Lee, Niels C. Bols;
A comparison of rainbow trout cell lines for their expression of the major histocompatibility complex genes and the induction of beta-2-microglobulin by dsRNA.
Fish Shellfish Immunol. 29:312-318(2010)

PubMed=22281180; DOI=10.1016/j.tiv.2012.01.001
Aude Kienzler, Xavier Tronchere, Alain Devaux, Sylvie Bony;
Assessment of RTG-W1, RTL-W1, and PLHC-1 fish cell lines for genotoxicity testing of environmental pollutants by means of a Fpg-modified comet assay.
Toxicol. In Vitro 26:500-510(2012)

PubMed=23305652; DOI=10.1016/j.tice.2012.10.006
Fernanda Malhao, Ralph Urbatzka, Jose Maria Navas, Catarina Cruzeiro, Rogerio Alves Ferreira Monteiro, Eduardo Rocha;
Cytological, immunocytochemical, ultrastructural and growth characterization of the rainbow trout liver cell line RTL-W1.
Tissue Cell 45:159-174(2013)

PubMed=24357037; DOI=10.1007/s11626-013-9720-3
Nguyen T.K. Vo, Mary Rose Bufalino, Kurtis D. Hartlen, Vladimir Kitaev, Lucy E.J. Lee;
Cytotoxicity evaluation of silica nanoparticles using fish cell lines.
In Vitro Cell. Dev. Biol. Anim. 50:427-438(2014)

PubMed=28374170; DOI=10.1007/s11626-017-0142-5
Niels C. Bols, Phuc H. Pham, Vivian R. Dayeh, Lucy E.J. Lee;
Invitromatics, invitrome, and invitroomics: introduction of three new terms for in vitro biology and illustration of their use with the cell lines from rainbow trout.
In Vitro Cell. Dev. Biol. Anim. 53:383-405(2017)

PubMed=29268113; DOI=10.1016/j.ecoenv.2017.12.027
Pauline Pannetier, Laura Fuster, Christelle Clerandeau, Camille Lacroix, Pierre-Yves Gourves, Jerome Cachot, Benedicte Morin;
Usefulness of RTL-W1 and OLCAB-e3 fish cell lines and multiple endpoint measurements for toxicity evaluation of unknown or complex mixture of chemicals.
Ecotoxicol. Environ. Saf. 150:40-48(2018)

PubMed=33053677; DOI=10.3390/pathogens9100833; PMCID=PMC7601784
Phuc H. Pham, Ehab Misk, Fotini Papazotos, Ginny Jones, Mark P. Polinski, Elena Contador, Spencer Russell, Kyle A. Garver, John S. Lumsden, Niels C. Bols;
Screening of fish cell lines for piscine orthoreovirus-1 (PRV-1) amplification: identification of the non-supportive PRV-1 invitrome.
Pathogens 9:833.1-833.25(2020)

Cross-references
Encyclopedic resources Wikidata; Q54951418
Entry history
Entry creation06-May-2013
Last entry update29-Jun-2023
Version number17