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Cellosaurus RTL-W1 (CVCL_L011)

[Text version]
Cell line name RTL-W1
Synonyms Rainbow Trout Liver-Waterloo 1
Accession CVCL_L011
Resource Identification Initiative To cite this cell line use: RTL-W1 (RRID:CVCL_L011)
Comments Group: Fish cell line.
Doubling time: 98.9 hours (PubMed=29268113).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) (NCBI Taxonomy: 8022)
Sex of cell Male
Age at sampling 4Y
Category Spontaneously immortalized cell line

PubMed=8299006; DOI=10.1007/BF00755606
Lee L.E.J., Clemons J.H., Bechtel D.G., Caldwell S.J., Han K.-B., Pasitschniak-Arts M., Mosser D.D., Bols N.C.
Development and characterization of a rainbow trout liver cell line expressing cytochrome P450-dependent monooxygenase activity.
Cell Biol. Toxicol. 9:279-294(1993)

PubMed=7766144; DOI=10.1007/BF00749903
Bols N.C., Ganassin R.C., Tom D.J., Lee L.E.J.
Growth of fish cell lines in glutamine-free media.
Cytotechnology 16:159-166(1994)

PubMed=11501281; DOI=10.1002/tox.1039
Nehls S., Segner H.
Detection of DNA damage in two cell lines from rainbow trout, RTG-2 and RTL-W1, using the comet assay.
Environ. Toxicol. 16:321-329(2001)

PubMed=19002917; DOI=10.1023/A:1020516804173
Perry G.M.L., McDonald G.J., Ferguson M.M., Ganassin R.C., Bols N.C.
Characterization of rainbow trout cell lines using microsatellite DNA profiling.
Cytotechnology 37:143-151(2001)

Bols N.C., Dayeh V.R., Lee L.E.J., Schirmer K.
Use of fish cell lines in the toxicology and ecotoxicology of fish Piscine cell lines in environmental toxicology.
(In) Biochemistry and molecular biology of fishes, Vol. 6; Mommsen T.P., Moon T.W. (eds.); pp.43-84; Elsevier; Amsterdam (2005)

PubMed=20420918; DOI=10.1016/j.fsi.2010.04.007
Kawano A., Kales S.C., Fujiki K., DeWitte-Orr S.J., Dixon B., Lee L.E.J., Bols N.C.
A comparison of rainbow trout cell lines for their expression of the major histocompatibility complex genes and the induction of beta-2-microglobulin by dsRNA.
Fish Shellfish Immunol. 29:312-318(2010)

PubMed=22281180; DOI=10.1016/j.tiv.2012.01.001
Kienzler A., Tronchere X., Devaux A., Bony S.
Assessment of RTG-W1, RTL-W1, and PLHC-1 fish cell lines for genotoxicity testing of environmental pollutants by means of a Fpg-modified comet assay.
Toxicol. In Vitro 26:500-510(2012)

PubMed=23305652; DOI=10.1016/j.tice.2012.10.006
Malhao F., Urbatzka R., Navas J.M., Cruzeiro C., Monteiro R.A.F., Rocha E.
Cytological, immunocytochemical, ultrastructural and growth characterization of the rainbow trout liver cell line RTL-W1.
Tissue Cell 45:159-174(2013)

PubMed=24357037; DOI=10.1007/s11626-013-9720-3
Vo N.T.K., Bufalino M.R., Hartlen K.D., Kitaev V., Lee L.E.J.
Cytotoxicity evaluation of silica nanoparticles using fish cell lines.
In Vitro Cell. Dev. Biol. Anim. 50:427-438(2014)

PubMed=28374170; DOI=10.1007/s11626-017-0142-5
Bols N.C., Pham P.H., Dayeh V.R., Lee L.E.J.
Invitromatics, invitrome, and invitroomics: introduction of three new terms for in vitro biology and illustration of their use with the cell lines from rainbow trout.
In Vitro Cell. Dev. Biol. Anim. 53:383-405(2017)

PubMed=29268113; DOI=10.1016/j.ecoenv.2017.12.027
Pannetier P., Fuster L., Clerandeau C., Lacroix C., Gourves P.-Y., Cachot J., Morin B.
Usefulness of RTL-W1 and OLCAB-e3 fish cell lines and multiple endpoint measurements for toxicity evaluation of unknown or complex mixture of chemicals.
Ecotoxicol. Environ. Saf. 150:40-48(2017)

PubMed=33053677; DOI=10.3390/pathogens9100833
Pham P.H., Misk E., Papazotos F., Jones G., Polinski M.P., Contador E., Russell S., Garver K.A., Lumsden J.S., Bols N.C.
Screening of fish cell lines for piscine orthoreovirus-1 (PRV-1) amplification: identification of the non-supportive PRV-1 invitrome.
Pathogens 9:833.1-833.25(2020)

Encyclopedic resources Wikidata; Q54951418
Entry history
Entry creation06-May-2013
Last entry update29-Jun-2023
Version number17