ID   RTL-W1
AC   CVCL_L011
SY   Rainbow Trout Liver-Waterloo 1
DR   Wikidata; Q54951418
RX   DOI=10.1016/S1873-0140(05)80005-0;
RX   PubMed=7766144;
RX   PubMed=8299006;
RX   PubMed=11501281;
RX   PubMed=19002917;
RX   PubMed=20420918;
RX   PubMed=22281180;
RX   PubMed=23305652;
RX   PubMed=24357037;
RX   PubMed=28374170;
RX   PubMed=29268113;
RX   PubMed=33053677;
CC   Group: Fish cell line.
CC   Doubling time: 98.9 hours (PubMed=29268113).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Cell type: Epithelial cell; CL=CL_0000066.
OX   NCBI_TaxID=8022; ! Oncorhynchus mykiss (Rainbow trout)
SX   Male
AG   4Y
CA   Spontaneously immortalized cell line
DT   Created: 06-05-13; Last updated: 29-06-23; Version: 17
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RX   DOI=10.1016/S1873-0140(05)80005-0;
RA   Bols N.C., Dayeh V.R., Lee L.E.J., Schirmer K.;
RT   "Use of fish cell lines in the toxicology and ecotoxicology of fish.
RT   Piscine cell lines in environmental toxicology.";
RL   (In) Biochemistry and molecular biology of fishes, Vol. 6; Mommsen T.P., Moon T.W. (eds.); pp.43-84; Elsevier; Amsterdam (2005).
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RX   PubMed=7766144; DOI=10.1007/BF00749903;
RA   Bols N.C., Ganassin R.C., Tom D.J., Lee L.E.J.;
RT   "Growth of fish cell lines in glutamine-free media.";
RL   Cytotechnology 16:159-166(1994).
//
RX   PubMed=8299006; DOI=10.1007/BF00755606;
RA   Lee L.E.J., Clemons J.H., Bechtel D.G., Caldwell S.J., Han K.-B.,
RA   Pasitschniak-Arts M., Mosser D.D., Bols N.C.;
RT   "Development and characterization of a rainbow trout liver cell line
RT   expressing cytochrome P450-dependent monooxygenase activity.";
RL   Cell Biol. Toxicol. 9:279-294(1993).
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RX   PubMed=11501281; DOI=10.1002/tox.1039;
RA   Nehls S., Segner H.;
RT   "Detection of DNA damage in two cell lines from rainbow trout, RTG-2
RT   and RTL-W1, using the comet assay.";
RL   Environ. Toxicol. 16:321-329(2001).
//
RX   PubMed=19002917; DOI=10.1023/A:1020516804173;
RA   Perry G.M.L., McDonald G.J., Ferguson M.M., Ganassin R.C., Bols N.C.;
RT   "Characterization of rainbow trout cell lines using microsatellite DNA
RT   profiling.";
RL   Cytotechnology 37:143-151(2001).
//
RX   PubMed=20420918; DOI=10.1016/j.fsi.2010.04.007;
RA   Kawano A., Kales S.C., Fujiki K., DeWitte-Orr S.J., Dixon B.,
RA   Lee L.E.J., Bols N.C.;
RT   "A comparison of rainbow trout cell lines for their expression of the
RT   major histocompatibility complex genes and the induction of
RT   beta-2-microglobulin by dsRNA.";
RL   Fish Shellfish Immunol. 29:312-318(2010).
//
RX   PubMed=22281180; DOI=10.1016/j.tiv.2012.01.001;
RA   Kienzler A., Tronchere X., Devaux A., Bony S.;
RT   "Assessment of RTG-W1, RTL-W1, and PLHC-1 fish cell lines for
RT   genotoxicity testing of environmental pollutants by means of a
RT   Fpg-modified comet assay.";
RL   Toxicol. In Vitro 26:500-510(2012).
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RX   PubMed=23305652; DOI=10.1016/j.tice.2012.10.006;
RA   Malhao F., Urbatzka R., Navas J.M., Cruzeiro C., Monteiro R.A.F.,
RA   Rocha E.;
RT   "Cytological, immunocytochemical, ultrastructural and growth
RT   characterization of the rainbow trout liver cell line RTL-W1.";
RL   Tissue Cell 45:159-174(2013).
//
RX   PubMed=24357037; DOI=10.1007/s11626-013-9720-3;
RA   Vo N.T.K., Bufalino M.R., Hartlen K.D., Kitaev V., Lee L.E.J.;
RT   "Cytotoxicity evaluation of silica nanoparticles using fish cell
RT   lines.";
RL   In Vitro Cell. Dev. Biol. Anim. 50:427-438(2014).
//
RX   PubMed=28374170; DOI=10.1007/s11626-017-0142-5;
RA   Bols N.C., Pham P.H., Dayeh V.R., Lee L.E.J.;
RT   "Invitromatics, invitrome, and invitroomics: introduction of three new
RT   terms for in vitro biology and illustration of their use with the cell
RT   lines from rainbow trout.";
RL   In Vitro Cell. Dev. Biol. Anim. 53:383-405(2017).
//
RX   PubMed=29268113; DOI=10.1016/j.ecoenv.2017.12.027;
RA   Pannetier P., Fuster L., Clerandeau C., Lacroix C., Gourves P.-Y.,
RA   Cachot J., Morin B.;
RT   "Usefulness of RTL-W1 and OLCAB-e3 fish cell lines and multiple
RT   endpoint measurements for toxicity evaluation of unknown or complex
RT   mixture of chemicals.";
RL   Ecotoxicol. Environ. Saf. 150:40-48(2017).
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RX   PubMed=33053677; DOI=10.3390/pathogens9100833;
RA   Pham P.H., Misk E., Papazotos F., Jones G., Polinski M.P.,
RA   Contador E., Russell S., Garver K.A., Lumsden J.S., Bols N.C.;
RT   "Screening of fish cell lines for piscine orthoreovirus-1 (PRV-1)
RT   amplification: identification of the non-supportive PRV-1 invitrome.";
RL   Pathogens 9:833.1-833.25(2020).
//