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Cellosaurus Namalwa/MDR1 (CVCL_KU33)

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Cell line name Namalwa/MDR1
Synonyms Namalwa/mdr-1; NMDR1
Accession CVCL_KU33
Resource Identification Initiative To cite this cell line use: Namalwa/MDR1 (RRID:CVCL_KU33)
Comments Population: African; Kenyan.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:40; ABCB1.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0067 (Namalwa)
Sex of cell Female
Age at sampling Children
Category Cancer cell line
Publications

PubMed=7492789; DOI=10.1182/blood.V86.11.4286.bloodjournal86114286
Rosemary O'Connor, Chang-Nian Liu, Cynthia Ann Ferris, Braydon Charles Guild, Beverly A. Teicher, Christopher Corvi, Yi-Mao Liu, Robert John Arceci, Victor S. Goldmacher, John M. Lambert, Walter A. Blattler;
Anti-B4-blocked ricin synergizes with doxorubicin and etoposide on multidrug-resistant and drug-sensitive tumors.
Blood 86:4286-4294(1995)

PubMed=10632321
Maria-Ana Ghetie, Victor Ghetie, Ellen S. Vitetta;
Anti-CD19 antibodies inhibit the function of the P-gp pump in multidrug-resistant B lymphoma cells.
Clin. Cancer Res. 5:3920-3927(1999)

PubMed=18357372; DOI=10.3892/or.19.4.889
Iliodora Pop, Laurentiu Pop, Ellen S. Vitetta, Maria-Ana Ghetie;
Generation of multidrug resistant lymphoma cell lines stably expressing P-glycoprotein.
Oncol. Rep. 19:889-895(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_KU33
Encyclopedic resources Wikidata; Q54907451
Entry history
Entry creation22-Aug-2017
Last entry update10-Apr-2025
Version number13