ID   Namalwa/MDR1
AC   CVCL_KU33
SY   Namalwa/mdr-1; NMDR1
DR   cancercelllines; CVCL_KU33
DR   Wikidata; Q54907451
RX   PubMed=7492789;
RX   PubMed=10632321;
RX   PubMed=18357372;
CC   Population: African; Kenyan.
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: HGNC; 40; ABCB1.
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0067 ! Namalwa
SX   Female
AG   Children
CA   Cancer cell line
DT   Created: 22-08-17; Last updated: 05-10-23; Version: 9
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RX   PubMed=7492789; DOI=10.1182/blood.V86.11.4286.bloodjournal86114286;
RA   O'Connor R., Liu C.-N., Ferris C.A., Guild B.C., Teicher B.A., Corvi C.,
RA   Liu Y.-M., Arceci R.J., Goldmacher V.S., Lambert J.M., Blattler W.A.;
RT   "Anti-B4-blocked ricin synergizes with doxorubicin and etoposide on
RT   multidrug-resistant and drug-sensitive tumors.";
RL   Blood 86:4286-4294(1995).
//
RX   PubMed=10632321;
RA   Ghetie M.-A., Ghetie V., Vitetta E.S.;
RT   "Anti-CD19 antibodies inhibit the function of the P-gp pump in
RT   multidrug-resistant B lymphoma cells.";
RL   Clin. Cancer Res. 5:3920-3927(1999).
//
RX   PubMed=18357372; DOI=10.3892/or.19.4.889;
RA   Pop I., Pop L., Vitetta E.S., Ghetie M.-A.;
RT   "Generation of multidrug resistant lymphoma cell lines stably
RT   expressing P-glycoprotein.";
RL   Oncol. Rep. 19:889-895(2008).
//