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Cellosaurus Raji/18V (CVCL_KU31)

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Cell line name Raji/18V
Synonyms R18V
Accession CVCL_KU31
Resource Identification Initiative To cite this cell line use: Raji/18V (RRID:CVCL_KU31)
Comments Population: African; Nigerian.
Selected for resistance to: ChEBI; CHEBI_28445; Vincristine (VCR).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr234His (c.700T>C); ClinVar=VCV000376691; Zygosity=Heterozygous (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0511 (Raji)
Sex of cell Male
Age at sampling 11Y
Category Cancer cell line
Publications

PubMed=18357372; DOI=10.3892/or.19.4.889
Iliodora Pop, Laurentiu Pop, Ellen S. Vitetta, Maria-Ana Ghetie;
Generation of multidrug resistant lymphoma cell lines stably expressing P-glycoprotein.
Oncol. Rep. 19:889-895(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_KU31
Encyclopedic resources Wikidata; Q54949154
Entry history
Entry creation22-Aug-2017
Last entry update19-Dec-2024
Version number15