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Cellosaurus CellSensor irf1-bla TF1 (CVCL_KS74)

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Cell line name CellSensor irf1-bla TF1
Synonyms irf1-bla TF1; irf1-bla TF-1
Accession CVCL_KS74
Resource Identification Initiative To cite this cell line use: CellSensor irf1-bla TF1 (RRID:CVCL_KS74)
Comments Population: Japanese.
Characteristics: Transfected with a plasmid containing a beta-lactamase reporter gene under control of the irf-1 response element.
Characteristics: IL3 or CSF2 dependent.
Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; Bacillus cereus Bsr.
Genetic integration: Method=Transfection; Gene=UniProtKB; P62593; Escherichia coli beta-lactamase bla (Note=With p.Met1_Phe22del, p.Ala23Met, p.Val82Ile and p.Met184Val).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; HGNC:15868; ABHD12 + HGNC; HGNC:1537; CBFA2T3; Name(s)=CBFA2T3-ABHD12 (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Pro (c.182A>C); ClinVar=VCV000280409; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ile251Thrfs*94 (c.752delT); ClinVar=VCV001759367; Zygosity=Unspecified (from parent cell line).
Disease Erythroleukemia (NCIt: C7152)
Acute erythroid leukemia (ORDO: Orphanet_318)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0559 (TF-1)
Sex of cell Male
Age at sampling 35Y
Category Cancer cell line
Web pages Provider; Thermo Fisher; K1657; https://www.thermofisher.com/order/catalog/product/K1657
Cross-references
Cell line databases/resources cancercelllines; CVCL_KS74
Encyclopedic resources Wikidata; Q54809191
Entry history
Entry creation22-Aug-2017
Last entry update14-Aug-2025
Version number17