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Cellosaurus CellSensor IL-1-bla ECV304 (CVCL_KS70)

[Text version]
Cell line name CellSensor IL-1-bla ECV304
Synonyms IL-1-bla ECV304
Accession CVCL_KS70
Resource Identification Initiative To cite this cell line use: CellSensor IL-1-bla ECV304 (RRID:CVCL_KS70)
Comments Problematic cell line: Contaminated. Parent cell line (ECV-304) has been shown to be a T24 derivative.
Population: Caucasian; Swedish.
Characteristics: Transfected with a plasmid containing a beta-lactamase reporter gene which has been randomly integrated in the genome of ECV-304 and which has been selected for IL1-responsiveness.
Transfected with: UniProtKB; P62593; Escherichia coli beta-lactamase bla (with p.Met1_Phe22del, p.Ala23Met, p.Val82Ile and p.Met184Val).
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; 5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2029 (ECV-304)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
Web pages https://www.thermofisher.com/order/catalog/product/K1645
Cell line databases/resources cancercelllines; CVCL_KS70
Encyclopedic resources Wikidata; Q54809187
Entry history
Entry creation22-Aug-2017
Last entry update05-Oct-2023
Version number12