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Cellosaurus K562/NFAT-luc (CVCL_KS44)

[Text version]
Cell line name K562/NFAT-luc
Accession CVCL_KS44
Resource Identification Initiative To cite this cell line use: K562/NFAT-luc (RRID:CVCL_KS44)
Comments Population: Caucasian.
Characteristics: The luciferase reporter gene is under the control of multiple copies of the NFAT response element.
Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transfected with: UniProtKB; P08659; Firefly luciferase.
Discontinued: Thermofisher/Panomics; Catalog number RC0009.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Web pages https://www.affymetrix.com/support/technical/usb/package_inserts/RC0009_package_insert.pdf
Cross-references
Encyclopedic resources Wikidata; Q54899415
Entry history
Entry creation22-Aug-2017
Last entry update05-Oct-2023
Version number14