Cellosaurus logo
expasy logo

Cellosaurus sNF02.2 (CVCL_K280)

[Text version]
Cell line name sNF02.2
Synonyms sNF02-2
Accession CVCL_K280
Resource Identification Initiative To cite this cell line use: sNF02.2 (RRID:CVCL_K280)
Comments Doubling time: ~26 hours (ATCC=CRL-2885).
Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
Disease Malignant peripheral nerve sheath tumor (NCIt: C3798)
Neurofibromatosis type 1 (NCIt: C3273)
Malignant peripheral nerve sheath tumor (ORDO: Orphanet_3148)
Neurofibromatosis type 1 (ORDO: Orphanet_636)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 35Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-2885

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133820,23
D3S135815,17
D5S81812
D7S82010,11
D8S117912,15
D13S31711,14
D16S53911,12
D18S5112.3,15.3
D19S43313,15.2
D21S1131.2
FGA22,23
Penta D13
Penta E16,18
TH017,9
TPOX8,12
vWA16

Run an STR similarity search on this cell line
Web pages Provider; UF Innovate; 11276; https://web.archive.org/web/20150618074550/http://technologylicensing.research.ufl.edu/technologies/11276_human-schwann-cell-like-cell-line-snf02-2
Publications

PubMed=14762442; DOI=10.1038/sj.onc.1207068
Yi-Wen Li, Prakash K. Rao, Rong Wen, Ying Song, David F. Muir 4th, Margaret R. Wallace, Samantha J. van Horne, Gihan I. Tennekoon, Tom Kadesch;
Notch and Schwann cell transformation.
Oncogene 23:1146-1152(2004)

PubMed=22346343; DOI=10.4137/TOG.S8830; PMCID=PMC3273949
Dao-Chun Sun, Michael A. Tainsky, Ramsi Haddad;
Oncogene mutation survey in MPNST cell lines enhances the dominant role of hyperactive Ras in NF1 associated pro-survival and malignancy.
Transl. Oncogenomics 5:1-7(2012)

PubMed=28469964; PMCID=PMC5411799
Jian-Man Guo, Michael R. Grovola, Hong Xie, Grace E. Coggins, Patrick Duggan, Rukhsana Hasan, Jia-Le Huang, Danny W. Lin, Claire Song, Gabriela M. Witek, Simon Berritt ...Show all 13 authors... , David C. Schultz, Jeffrey Field; Show fewer authors
Comprehensive pharmacological profiling of neurofibromatosis cell lines.
Am. J. Cancer Res. 7:923-934(2017)

PubMed=32642732; DOI=10.1093/noajnl/vdz049; PMCID=PMC7317054
Alexander Pemov, Hua Li, William Presley, Margaret R. Wallace, David T. Miller;
Genetics of human malignant peripheral nerve sheath tumors.
Neurooncol. Adv. 2:i50-i61(2020)

Cross-references
Cell line collections (Providers) ATCC; CRL-2885
Biological sample resources BioSample; SAMN03471811
Encyclopedic resources Wikidata; Q54955056
Polymorphism and mutation databases Cosmic; 1644554
Entry history
Entry creation11-Feb-2013
Last entry update10-Apr-2025
Version number19