ID   sNF02.2
AC   CVCL_K280
SY   sNF02-2
DR   ATCC; CRL-2885
DR   BioSample; SAMN03471811
DR   Cosmic; 1644554
DR   Wikidata; Q54955056
RX   PubMed=14762442;
RX   PubMed=22346343;
RX   PubMed=28469964;
RX   PubMed=32642732;
WW   Provider; UF Innovate; 11276; https://web.archive.org/web/20150618074550/http://technologylicensing.research.ufl.edu/technologies/11276_human-schwann-cell-like-cell-line-snf02-2
CC   Doubling time: ~26 hours (ATCC=CRL-2885).
CC   Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
ST   Source(s): ATCC=CRL-2885
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 11,14
ST   D16S539: 11,12
ST   D18S51: 12.3,15.3
ST   D19S433: 13,15.2
ST   D21S11: 31.2
ST   D2S1338: 20,23
ST   D3S1358: 15,17
ST   D5S818: 12
ST   D7S820: 10,11
ST   D8S1179: 12,15
ST   FGA: 22,23
ST   Penta D: 13
ST   Penta E: 16,18
ST   TH01: 7,9
ST   TPOX: 8,12
ST   vWA: 16
DI   NCIt; C3798; Malignant peripheral nerve sheath tumor
DI   NCIt; C3273; Neurofibromatosis type 1
DI   ORDO; Orphanet_3148; Malignant peripheral nerve sheath tumor
DI   ORDO; Orphanet_636; Neurofibromatosis type 1
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   35Y
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 10-04-25; Version: 19
//
RX   PubMed=14762442; DOI=10.1038/sj.onc.1207068;
RA   Li, Yi-Wen
RA   Rao, Prakash K.
RA   Wen, Rong
RA   Song, Ying
RA   Muir, David F. 4th
RA   Wallace, Margaret R.
RA   van Horne, Samantha J.
RA   Tennekoon, Gihan I.
RA   Kadesch, Tom
RT   "Notch and Schwann cell transformation.";
RL   Oncogene 23:1146-1152(2004).
//
RX   PubMed=22346343; DOI=10.4137/TOG.S8830; PMCID=PMC3273949;
RA   Sun, Dao-Chun
RA   Tainsky, Michael A.
RA   Haddad, Ramsi
RT   "Oncogene mutation survey in MPNST cell lines enhances the dominant
RT   role of hyperactive Ras in NF1 associated pro-survival and
RT   malignancy.";
RL   Transl. Oncogenomics 5:1-7(2012).
//
RX   PubMed=28469964; PMCID=PMC5411799;
RA   Guo, Jian-Man
RA   Grovola, Michael R.
RA   Xie, Hong
RA   Coggins, Grace E.
RA   Duggan, Patrick
RA   Hasan, Rukhsana
RA   Huang, Jia-Le
RA   Lin, Danny W.
RA   Song, Claire
RA   Witek, Gabriela M.
RA   Berritt, Simon
RA   Schultz, David C.
RA   Field, Jeffrey
RT   "Comprehensive pharmacological profiling of neurofibromatosis cell
RT   lines.";
RL   Am. J. Cancer Res. 7:923-934(2017).
//
RX   PubMed=32642732; DOI=10.1093/noajnl/vdz049; PMCID=PMC7317054;
RA   Pemov, Alexander
RA   Li, Hua
RA   Presley, William
RA   Wallace, Margaret R.
RA   Miller, David T.
RT   "Genetics of human malignant peripheral nerve sheath tumors.";
RL   Neurooncol. Adv. 2:i50-i61(2020).
//