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Cellosaurus XR-1 (CVCL_K253)

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Cell line name XR-1
Synonyms CHO XR-1; CHO.XR-1; GM16147
Accession CVCL_K253
Resource Identification Initiative To cite this cell line use: XR-1 (RRID:CVCL_K253)
Comments Characteristics: Both alleles of Xrcc4 are deleted in this cell line.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_K254 (CHO 4364)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=6836453; DOI=10.1007/BF01543175
Thomas D. Stamato, Ronald Weinstein, Amato J. Giaccia, Laurie Mackenzie;
Isolation of cell cycle-dependent gamma ray-sensitive Chinese hamster ovary cell.
Somatic Cell Genet. 9:165-173(1983)

PubMed=2164147; DOI=10.1016/0921-8777(90)90034-3
Amato J. Giaccia, Renate A. MacLaren, Nicholas Denko, Dave Nicolaou, Thomas D. Stamato;
Increased sensitivity to killing by restriction enzymes in the XR-1 DNA double-strand break repair-deficient mutant.
Mutat. Res. 236:67-76(1990)

PubMed=10047779; DOI=10.1016/S0921-8777(98)00063-9
Margaret Bryans, Mary Carmen Valenzano, Thomas D. Stamato;
Absence of DNA ligase IV protein in XR-1 cells: evidence for stabilization by XRCC4.
Mutat. Res. 433:53-58(1999)

Cross-references
Cell line collections (Providers) Coriell; GM16147
RCB; RCB2331
Cell line databases/resources CLO; CLO_0019811
CLO; CLO_0050426
Encyclopedic resources Wikidata; Q54995035
Entry history
Entry creation11-Feb-2013
Last entry update30-Jan-2024
Version number10