ID   XR-1
AC   CVCL_K253
SY   CHO XR-1; CHO.XR-1; GM16147
DR   CLO; CLO_0019811
DR   CLO; CLO_0050426
DR   Coriell; GM16147
DR   RCB; RCB2331
DR   Wikidata; Q54995035
RX   PubMed=2164147;
RX   PubMed=6836453;
RX   PubMed=10047779;
CC   Characteristics: Both alleles of Xrcc4 are deleted in this cell line.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_K254 ! CHO 4364
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 11-02-13; Last updated: 30-01-24; Version: 10
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RX   PubMed=2164147; DOI=10.1016/0921-8777(90)90034-3;
RA   Giaccia A.J., MacLaren R.A., Denko N., Nicolaou D., Stamato T.D.;
RT   "Increased sensitivity to killing by restriction enzymes in the XR-1
RT   DNA double-strand break repair-deficient mutant.";
RL   Mutat. Res. 236:67-76(1990).
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RX   PubMed=6836453; DOI=10.1007/BF01543175;
RA   Stamato T.D., Weinstein R., Giaccia A.J., Mackenzie L.;
RT   "Isolation of cell cycle-dependent gamma ray-sensitive Chinese hamster
RT   ovary cell.";
RL   Somatic Cell Genet. 9:165-173(1983).
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RX   PubMed=10047779; DOI=10.1016/S0921-8777(98)00063-9;
RA   Bryans M., Valenzano M.C., Stamato T.D.;
RT   "Absence of DNA ligase IV protein in XR-1 cells: evidence for
RT   stabilization by XRCC4.";
RL   Mutat. Res. 433:53-58(1999).
//