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Cellosaurus M21L22 (CVCL_JZ14)

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Cell line name M21L22
Synonyms M21-L22; M21-L variant 12
Accession CVCL_JZ14
Resource Identification Initiative To cite this cell line use: M21L22 (RRID:CVCL_JZ14)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:6150; ITGAV.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: Metastatic; Not specified.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (from parent cell line).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_JZ12 (M21L)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=1376331; DOI=10.1172/JCI115811; PMCID=PMC295910
Brunhilde Felding-Habermann, Barbara M. Mueller, Cynthia A. Romerdahl, David A. Cheresh;
Involvement of integrin alpha V gene expression in human melanoma tumorigenicity.
J. Clin. Invest. 89:2018-2022(1992)

Cross-references
Cell line databases/resources cancercelllines; CVCL_JZ14
Encyclopedic resources Wikidata; Q54903522
Entry history
Entry creation22-Aug-2017
Last entry update14-Aug-2025
Version number10