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Cellosaurus HepG2-rNTCP-eGFP (CVCL_JY38)

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Cell line name HepG2-rNTCP-eGFP
Synonyms HepG2 FLAG-Ntcp-EGFP
Accession CVCL_JY38
Resource Identification Initiative To cite this cell line use: HepG2-rNTCP-eGFP (RRID:CVCL_JY38)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection; Gene=RGD; 3681; Slc10a1 (Note=With a N-terminal FLAG tag).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=20539008; DOI=10.1152/ajpgi.00180.2010
Claudia Stross, Angelika Helmer, Katrin Weissenberger, Boris Gorg, Verena Keitel, Dieter Haussinger, Ralf Kubitz;
Protein kinase C induces endocytosis of the sodium taurocholate cotransporting polypeptide.
Am. J. Physiol. Gastrointest. Liver Physiol. 299:G320-G328(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_JY38
Encyclopedic resources Wikidata; Q54882856
Entry history
Entry creation22-Aug-2017
Last entry update14-Aug-2025
Version number17