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Cellosaurus HBLAK (CVCL_JQ59)

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Cell line name HBLAK
Accession CVCL_JQ59
Resource Identification Initiative To cite this cell line use: HBLAK (RRID:CVCL_JQ59)
Comments Doubling time: ~30 hours (PubMed=28035326).
Omics: Genomics; Whole exome sequencing.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Cell type: Urothelial cell; CL=CL_0000731.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Unspecified (PubMed=28035326).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=28035326).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 80Y
Category Spontaneously immortalized cell line
STR profile Source(s): PubMed=28035326

Markers:
AmelogeninX,Y
CSF1PO12
D1S165615,18
D2S44110,11
D2S133819,25
D3S135817,18
D5S81811
D7S82010,12
D8S117911,13
D10S124813,14
D12S39117,21
D13S31710,12
D16S53911,12
D18S5112,16
D19S43314,15
D21S1130,33.2
D22S104513,16
FGA20,22
SE3324.2,27.2
TH016,7
TPOX8,11
vWA13,18

Run an STR similarity search on this cell line
Web pages Provider; CELLnTEC; -; https://cellntec.com/products/hblak/
Publications

PubMed=28035326; DOI=10.3233/BLC-160065; PMCID=PMC5181672
Michele J. Hoffmann, Evangelia Koutsogiannouli, Margaretha A. Skowron, Maria Pinkerneil, Gunter Niegisch, Artur Brandt, Stefanie Stepanow, Harald Rieder, Wolfgang Arthur Schulz;
The new immortalized uroepithelial cell line HBLAK contains defined genetic aberrations typical of early stage urothelial tumors.
Bladder Cancer 2:449-463(2016)

Cross-references
Encyclopedic resources Wikidata; Q54881443
Entry history
Entry creation22-Aug-2017
Last entry update10-Apr-2025
Version number13