ID   HBLAK
AC   CVCL_JQ59
DR   Wikidata; Q54881443
RX   PubMed=28035326;
WW   https://cellntec.com/products/hblak/
CC   Doubling time: ~30 hours (PubMed=28035326).
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Unspecified (PubMed=28035326).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=28035326).
CC   Omics: Deep exome analysis.
CC   Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
CC   Cell type: Urothelial cell; CL=CL_0000731.
ST   Source(s): PubMed=28035326
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D10S1248: 13,14
ST   D12S391: 17,21
ST   D13S317: 10,12
ST   D16S539: 11,12
ST   D18S51: 12,16
ST   D19S433: 14,15
ST   D1S1656: 15,18
ST   D21S11: 30,33.2
ST   D22S1045: 13,16
ST   D2S1338: 19,25
ST   D2S441: 10,11
ST   D3S1358: 17,18
ST   D5S818: 11
ST   D7S820: 10,12
ST   D8S1179: 11,13
ST   FGA: 20,22
ST   SE33: 24.2,27.2
ST   TH01: 6,7
ST   TPOX: 8,11
ST   vWA: 13,18
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   80Y
CA   Spontaneously immortalized cell line
DT   Created: 22-08-17; Last updated: 29-06-23; Version: 11
//
RX   PubMed=28035326; DOI=10.3233/BLC-160065;
RA   Hoffmann M.J., Koutsogiannouli E., Skowron M.A., Pinkerneil M.,
RA   Niegisch G., Brandt A., Stepanow S., Rieder H., Schulz W.A.;
RT   "The new immortalized uroepithelial cell line HBLAK contains defined
RT   genetic aberrations typical of early stage urothelial tumors.";
RL   Bladder Cancer 2:449-463(2016).
//