PubMed=2866223; DOI=10.1084/jem.162.6.2169; PMCID=PMC2187984
Michiyuki Maeda, Akira Shimizu, Koichi Ikuta, Hiroyuki Okamoto, Mari Kashihara, Takashi Uchiyama, Tasuku Honjo, Junji Yodoi;
Origin of human T-lymphotrophic virus I-positive T cell lines in adult T cell leukemia. Analysis of T cell receptor gene rearrangement.
J. Exp. Med. 162:2169-2174(1985)

PubMed=7662981; DOI=10.1182/blood.V86.6.2350.bloodjournal8662350
Kazunori Imada, Akifumi Takaori-Kondo, Tsuyoshi Akagi, Kunitada Shimotohno, Kazuo Sugamura, Toshio Hattori, Hirohiko Yamabe, Minoru Okuma, Takashi Uchiyama;
Tumorigenicity of human T-cell leukemia virus type I-infected cell lines in severe combined immunodeficient mice and characterization of the cells proliferating in vivo.
Blood 86:2350-2357(1995)

PubMed=15638850; DOI=10.1111/j.1365-2141.2004.05255.x
Maki Ueda, Kazunori Imada, Akihiro Imura, Hikari Koga, Masakatsu Hishizawa, Takashi Uchiyama;
Expression of functional interleukin-21 receptor on adult T-cell leukaemia cells.
Br. J. Haematol. 128:169-176(2005)

PubMed=16314839; DOI=10.1038/sj.onc.1209256
Mohammed Kaimul Ahsan, Hiroshi Masutani, Yoshimi Yamaguchi, Yong-Chul Kim, Kisato Nosaka, Masao Matsuoka, Yumiko Nishinaka, Michiyuki Maeda, Junji Yodoi;
Loss of interleukin-2-dependency in HTLV-I-infected T cells on gene silencing of thioredoxin-binding protein-2.
Oncogene 25:2181-2191(2006)

PubMed=32210945; DOI=10.3389/fmicb.2020.00356; PMCID=PMC7067701
Michiyuki Maeda, Junko Tanabe-Shibuya, Paola Miyazato, Hiroshi Masutani, Jun-ichirou Yasunaga, Kazumasa Usami, Akira Shimizu, Masao Matsuoka;
IL-2/IL-2 receptor pathway plays a crucial role in the growth and malignant transformation of HTLV-1-infected T cells to develop adult T-cell leukemia.
Front. Microbiol. 11:356.1-356.17(2020)

PubMed=34794206; DOI=10.1111/cas.15204; PMCID=PMC8819293
Emi Ikebe, Shunsuke Shimosaki, Hiroo Hasegawa, Hidekatsu Iha, Yoshiyuki Tsukamoto, Yu Wang, Daisuke Sasaki, Yoshitaka Imaizumi, Yasushi Miyazaki, Katsunori Yanagihara, Isao Hamaguchi, Kazuhiro Morishita;
TAS-116 (pimitespib), a heat shock protein 90 inhibitor, shows efficacy in preclinical models of adult T-cell leukemia.
Cancer Sci. 113:684-696(2022)