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Cellosaurus NT2.5 LI3 (CVCL_JA64)

[Text version]
Cell line name NT2.5 LI3
Synonyms LI3; Li3
Accession CVCL_JA64
Resource Identification Initiative To cite this cell line use: NT2.5 LI3 (RRID:CVCL_JA64)
Comments Characteristics: Produced by injection of NT2.5 cells into the left cardiac ventricle of neu-N mice resulting in the formation of metastatic lesions in liver. These metastatic lesions were established in cell culture and subsequently reinjected into neu-N mice. This selection process was repeated until sublines with a liver preference were obtained.
Genetic integration: Method=Transgenic mouse; Gene=RGD; 2561; Erbb2.
Omics: Transcriptomics; Microarray.
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: FVB/N-Tg(MMTVneu)202Mul/J transgenic.
Hierarchy Parent: CVCL_JA63 (NT2.5 LI1)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=19642106; DOI=10.1002/ijc.24780
Lau W.M., Weber K.L., Doucet M., Chou Y.-T., Brady K., Kowalski J., Tsai H.-L., Yang J., Kominsky S.L.
Identification of prospective factors promoting osteotropism in breast cancer: a potential role for CITED2.
Int. J. Cancer 126:876-884(2010)

Cross-references
Encyclopedic resources Wikidata; Q54931109
Gene expression databases GEO; GSM1155328
Entry history
Entry creation15-May-2017
Last entry update10-Apr-2025
Version number5