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Cellosaurus HBT-39b (CVCL_J652)

[Text version]
Cell line name HBT-39b
Synonyms HBT-39B; HBT39B; HBT39b; HBT-39; HT-39
Accession CVCL_J652
Resource Identification Initiative To cite this cell line use: HBT-39b (RRID:CVCL_J652)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=884688; PubMed=1246601; PubMed=4469665; PubMed=6451928; PubMed=20143388). Originally thought to originate from a breast carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00053.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=4122211; DOI=10.1093/jnci/50.4.849
Ernest J. Plata, Tadao Aoki, Diane D. Robertson, Elizabeth W. Chu, Brenda Isen Gerwin;
An established cultured cell line (HBT-39) from human breast carcinoma.
J. Natl. Cancer Inst. 50:849-862(1973)

PubMed=4469665; DOI=10.1126/science.184.4141.1093
Walter Anthony Nelson-Rees, Robert R. Flandermeyer, Paula K. Hawthorne;
Banded marker chromosomes as indicators of intraspecies cellular contamination.
Science 184:1093-1096(1974)

DOI=10.1007/978-1-4757-1647-4_13
June Lee Biedler;
Chromosome abnormalities in human tumor cells in culture.
(In book chapter) Human tumor cells in vitro; Fogh, Jorgen (eds.); pp.359-394; Springer; New York; USA (1975)

PubMed=1000504
Marc E. Lippman, Gall Bolan, Karen Huff;
The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long-term tissue culture.
Cancer Res. 36:4595-4601(1976)

PubMed=1000506
Marc E. Lippman, Gall Bolan, Karen Huff;
The effects of androgens and antiandrogens on hormone-responsive human breast cancer in long-term tissue culture.
Cancer Res. 36:4610-4618(1976)

PubMed=1246601; DOI=10.1126/science.1246601
Walter Anthony Nelson-Rees, Robert R. Flandermeyer;
HeLa cultures defined.
Science 191:96-98(1976)

PubMed=884688
Walter Anthony Nelson-Rees;
Three papers on hormones and breast cancer in vitro.
Cancer Res. 37:3464-3465(1977)

PubMed=6451928; DOI=10.1126/science.6451928
Walter Anthony Nelson-Rees, David W. Daniels, Robert R. Flandermeyer;
Cross-contamination of cells in culture.
Science 212:446-452(1981)

CLPUB00262
Michael Gold;
A conspiracy of cells. One woman's immortal legacy and the medical scandal it caused.
(In book) ISBN 9780887060991; pp.1-171; State University of New York Press; Albany; USA (1986)

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Biological sample resources BioSample; SAMN03151700
Encyclopedic resources Wikidata; Q54881459
Entry history
Entry creation11-Feb-2013
Last entry update10-Apr-2025
Version number22