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Cellosaurus STC-1 (CVCL_J405)

[Text version]
Cell line name STC-1
Accession CVCL_J405
Resource Identification Initiative To cite this cell line use: STC-1 (RRID:CVCL_J405)
Comments Doubling time: 54 hours (PubMed=29787051).
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P68835; Murine polyomavirus (strain A2) (MPyV) small T antigen (PyST).
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 10636; Murine polyomavirus (strain A2) (MPyV).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Small intestine, duodenum; UBERON=UBERON_0002114.
Disease Neuroendocrine adenoma of the mouse intestinal tract (NCIt: C22150)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6J double transgenic RIP1Tag2/Rip2pyST1.
Hierarchy Children:
CVCL_J404 (STC 6-14)CVCL_C6ND (STC-1 pGIP/Neo)
Sex of cell Sex unspecified
Age at sampling 10-13W
Category Cancer cell line
Publications

PubMed=2162628; PMCID=PMC1877573
Guido Rindi, Seth G.N. Grant, Yiangos Yiangou, Mohammed A. Ghatei, Stephen Robert Bloom, Victoria L. Bautch, Enrico Solcia, Julia Margaret Polak;
Development of neuroendocrine tumors in the gastrointestinal tract of transgenic mice. Heterogeneity of hormone expression.
Am. J. Pathol. 136:1349-1363(1990)

PubMed=1654206
Seth G.N. Grant, Irving Seidman, Douglas Hanahan, Victoria L. Bautch;
Early invasiveness characterizes metastatic carcinoid tumors in transgenic mice.
Cancer Res. 51:4917-4923(1991)

PubMed=18708196; DOI=10.1016/j.jss.2008.03.055
Gilles Poncet, Karine Villaume, Thomas Walter, Celine Pourreyron, Aurelie Theillaumas, Florian Lepinasse, Valerie Hervieu, Martine Cordier-Bussat, Jean-Yves Scoazec, Colette Roche;
Angiogenesis and tumor progression in neuroendocrine digestive tumors.
J. Surg. Res. 154:68-77(2009)

PubMed=22538498; DOI=10.1159/000338793
Simona Grozinsky-Glasberg, Ilan Shimon, Hadara Rubinfeld;
The role of cell lines in the study of neuroendocrine tumors.
Neuroendocrinology 96:173-187(2012)

PubMed=29787051; DOI=10.1007/978-3-319-16104-4_19
Triona McCarthy, Brian D. Green, Danielle Calderwood, Anna L. Gillespie, John F. Cryan, Linda Giblin;
STC-1 cells.
(In book chapter) The impact of food bioactives on health. In vitro and ex vivo models; Verhoeckx, Kitty & Cotter, Paul David & Lopez-Exposito, Ivan & Kleiveland, Charlotte Ramstad & Lea, Tor & Mackie, Alan Robert & Requena, Teresa & Swiatecka, Dominika & Wichers, Harry J. (eds.); pp.211-220; Springer; Cham; Switzerland (2015)

PubMed=28870797; DOI=10.1016/j.peptides.2017.08.010
Anna L. Gillespie, Xiao-Bei Pan, Anna Marco-Ramell, Caroline Meharg, Brian D. Green;
Detailed characterisation of STC-1 cells and the pGIP/Neo sub-clone suggests the incretin hormones are translationally regulated.
Peptides 96:20-30(2017)

Cross-references
Cell line collections (Providers) ATCC; CRL-3254
Anatomy/cell type resources BTO; BTO_0003584
Encyclopedic resources Wikidata; Q54970558
Entry history
Entry creation11-Feb-2013
Last entry update14-Aug-2025
Version number16