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Cellosaurus FL-18-EB (CVCL_J353)

[Text version]
Cell line name FL-18-EB
Synonyms FL-18EB
Accession CVCL_J353
Resource Identification Initiative To cite this cell line use: FL-18-EB (RRID:CVCL_J353)
Comments Population: Japanese.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 990; BCL2 + HGNC; 5477; IGH; Name(s)=IGH-BCL2 (PubMed=12967475).
Disease Follicular lymphoma (NCIt: C3209)
Follicular lymphoma (ORDO: Orphanet_545)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_8093 ! FL-18
Sex of cell Male
Age at sampling 68Y
Category Transformed cell line

PubMed=2822175; DOI=10.1182/blood.V70.5.1619.1619
Doi S., Ohno H., Tatsumi E., Arita Y., Kamesaki H., Fukuhara S., Nishikori M., Miwa H., Kita K., Hatanaka M., Honjo T., Fujii H., Uchino H.
Lymphoma cell line (FL-18) and Epstein-Barr virus-carrying cell line (FL-18-EB) obtained from a patient with follicular lymphoma: monoclonal derivation and different properties.
Blood 70:1619-1623(1987)

PubMed=3034807; DOI=10.1002/ijc.2910390622
Ohno H., Fukuhara S., Takahashi R., Mihara K.-i., Sugiyama T., Doi S., Uchino H., Toyoshima K.
c-yes and bcl-2 genes located on 18q21.3 in a follicular lymphoma cell line carrying a t(14;18) chromosomal translocation.
Int. J. Cancer 39:785-788(1987)

Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=12967475; DOI=10.1111/j.1349-7006.2003.tb01518.x
Maesako Y., Uchiyama T., Ohno H.
Comparison of gene expression profiles of lymphoma cell lines from transformed follicular lymphoma, Burkitt's lymphoma and de novo diffuse large B-cell lymphoma.
Cancer Sci. 94:774-781(2003)

Encyclopedic resources Wikidata; Q54834953
Entry history
Entry creation11-Feb-2013
Last entry update29-Jun-2023
Version number15