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Cellosaurus SK-MEL-2-Luc (CVCL_J266)

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Cell line name SK-MEL-2-Luc
Accession CVCL_J266
Resource Identification Initiative To cite this cell line use: SK-MEL-2-Luc (RRID:CVCL_J266)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: Metastatic; Thigh, skin; UBERON=UBERON_0004262.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly245Ser (c.733G>A); ClinVar=VCV000012365; Zygosity=Heterozygous (from parent cell line).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0069 (SK-MEL-2)
Sex of cell Male
Age at sampling 60Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1393

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81812,13
D7S82011,12
D13S31711
D16S5398,9
TH019
TPOX8,9
vWA17

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Cross-references
Cell line collections (Providers) JCRB; JCRB1393
JCRB; NIHS0640 - Discontinued
Cell line databases/resources cancercelllines; CVCL_J266
Encyclopedic resources Wikidata; Q54953907
Entry history
Entry creation11-Feb-2013
Last entry update14-Aug-2025
Version number25