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Cellosaurus DU-145-Luc (CVCL_J251)

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Cell line name DU-145-Luc
Accession CVCL_J251
Resource Identification Initiative To cite this cell line use: DU-145-Luc (RRID:CVCL_J251)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: Metastatic; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Asp84Tyr (c.250G>T) (p.Arg98Leu, c.293G>T); ClinVar=VCV000376306; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; p.Lys715Ter (c.2143A>T); ClinVar=VCV001786615; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Lys178fs*86 (c.532_536delAAGCC); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro223Leu (c.668C>T); ClinVar=VCV000234214; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val274Phe (c.820G>T); ClinVar=VCV000376674; Zygosity=Heterozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0105 (DU145)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1387

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81810,13
D7S8207,10,10.3,11
D13S31712,13
D16S53911,12,13
TH017
TPOX11
vWA17,18

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Cross-references
Cell line collections (Providers) JCRB; JCRB1387
JCRB; NIHS0655 - Discontinued
Cell line databases/resources cancercelllines; CVCL_J251
Encyclopedic resources Wikidata; Q54831565
Entry history
Entry creation11-Feb-2013
Last entry update14-Aug-2025
Version number23