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Cellosaurus BxPC-3-Luc#2 (CVCL_J246)

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Cell line name BxPC-3-Luc#2
Accession CVCL_J246
Resource Identification Initiative To cite this cell line use: BxPC-3-Luc#2 (RRID:CVCL_J246)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val487_Pro492delinsAla (c.1460_1474delGTGTAGGTGCTGTCA); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; None_reported; -; Zygosity=- (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0186 (BxPC-3)
Sex of cell Female
Age at sampling 61Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1448

Markers:
AmelogeninX
CSF1PO13
D5S81811
D7S82010,13
D13S31711
D16S5399,11
TH019
TPOX8
vWA14,18

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Cross-references
Cell line collections (Providers) JCRB; JCRB1448
JCRB; NIHS0702 - Discontinued
Cell line databases/resources cancercelllines; CVCL_J246
Encyclopedic resources Wikidata; Q54798760
Entry history
Entry creation11-Feb-2013
Last entry update14-Aug-2025
Version number22