Cellosaurus cell line NAMEC8 (CVCL

Cellosaurus NAMEC8 (CVCL_IZ69)

Cross-references
Cell line name	NAMEC8
Synonyms	NAMEC 8; N8; Naturally Arising MEsenchymal Cells 8
Accession	CVCL_IZ69
Resource Identification Initiative	To cite this cell line use: NAMEC8 (RRID:CVCL_IZ69)
Comments	Omics: Genomics; ChIP-seq; H3K9me2. Omics: Genomics; ChIP-seq; H3K9me3. Derived from site: In situ; Breast; UBERON=UBERON_0000310. Cell type: Mesenchymal cell; CL=CL_0008019.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Category	Spontaneously immortalized cell line
Publications	PubMed=24029232; DOI=10.1016/j.ccr.2013.08.005; PMCID=PMC4001722 Wai Leong Tam, Hai-Hui Lu, Joyce Y. Buikhuisen, Boon Seng Soh, Elgene Lim, Ferenc Reinhardt, Zhen-Hua Jeremy Wu, Jordan A. Krall, Brian Bierie, Wen-Jun Guo, Xi Chen ...Show all 15 authors... , Xiao-Le Shirley Liu, Myles A. Brown, Bing Lim, Robert Allan Weinberg; Show fewer authors Protein kinase C alpha is a central signaling node and therapeutic target for breast cancer stem cells. Cancer Cell 24:347-364(2013) PubMed=26941323; DOI=10.1126/science.aad3680; PMCID=PMC5131720 Diwakar R. Pattabiraman, Brian Bierie, Katharina Isabelle Kober, Prathapan Thiru, Jordan A. Krall, Christina Zill, Ferenc Reinhardt, Wai Leong Tam, Robert Allan Weinberg; Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability. Science 351:aad3680.1-aad3680.11(2016)
Encyclopedic resources	Wikidata; Q54907468
Gene expression databases	GEO; GSE74865
Entry history
Entry creation	15-May-2017
Last entry update	10-Apr-2025
Version number	6