ID   NAMEC8
AC   CVCL_IZ69
SY   NAMEC 8; N8; Naturally Arising MEsenchymal Cells 8
DR   GEO; GSE74865
DR   Wikidata; Q54907468
RX   PubMed=24029232;
RX   PubMed=26941323;
CC   Omics: Genomics; ChIP-seq; H3K9me2.
CC   Omics: Genomics; ChIP-seq; H3K9me3.
CC   Derived from site: In situ; Breast; UBERON=UBERON_0000310.
CC   Cell type: Mesenchymal cell; CL=CL_0008019.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
CA   Spontaneously immortalized cell line
DT   Created: 15-05-17; Last updated: 10-04-25; Version: 6
//
RX   PubMed=24029232; DOI=10.1016/j.ccr.2013.08.005; PMCID=PMC4001722;
RA   Tam W.L., Lu H.-H., Buikhuisen J.Y., Soh B.S., Lim E., Reinhardt F.,
RA   Wu Z.-H.J., Krall J.A., Bierie B., Guo W.-J., Chen X., Liu X.-L.S.,
RA   Brown M.A., Lim B., Weinberg R.A.;
RT   "Protein kinase C alpha is a central signaling node and therapeutic
RT   target for breast cancer stem cells.";
RL   Cancer Cell 24:347-364(2013).
//
RX   PubMed=26941323; DOI=10.1126/science.aad3680; PMCID=PMC5131720;
RA   Pattabiraman D.R., Bierie B., Kober K.I., Thiru P., Krall J.A.,
RA   Zill C., Reinhardt F., Tam W.L., Weinberg R.A.;
RT   "Activation of PKA leads to mesenchymal-to-epithelial transition and
RT   loss of tumor-initiating ability.";
RL   Science 351:aad3680.1-aad3680.11(2016).
//