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Cellosaurus PER-785 (CVCL_IZ03)

[Text version]
Cell line name PER-785
Synonyms PER-785A
Accession CVCL_IZ03
Resource Identification Initiative To cite this cell line use: PER-785 (RRID:CVCL_IZ03)
Comments Doubling time: 60 hours (PubMed=27443263).
Omics: Transcriptomics; RNAseq.
Miscellaneous: Sampling site from personal communication of Kotecha, Rishi S.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Disease Infant acute lymphoblastic leukemia with MLL rearrangement (NCIt: C122617)
Acute lymphoblastic leukemia (ORDO: Orphanet_513)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_IZ04 ! PER-785S
Sex of cell Female
Age at sampling 2M
Category Cancer cell line
STR profile Source(s): PubMed=27443263; PubMed=33937032

Markers:
AmelogeninX
CSF1PO11,12
D5S81811,12
D7S82011,13
D13S31711,12
D16S5399
D21S1130,30.2
TH016,7
TPOX8
vWA14

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Publications

PubMed=27443263; DOI=10.1038/leu.2016.165; PMCID=PMC5220136
Cruickshank M.N., Ford J., Cheung L.C., Heng J., Singh S., Wells J., Failes T.W., Arndt G.M., Smithers N., Prinjha R.K., Anderson D., Carter K.W., Gout A.M., Lassmann T., O'Reilly J., Cole C.H., Kotecha R.S., Kees U.R.
Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsin.
Leukemia 31:40-50(2017)

PubMed=33937032; DOI=10.3389/fonc.2021.631594; PMCID=PMC8082024
Cheung L.C., de Kraa R., Oommen J., Chua G.-A., Singh S., Hughes A.M., Ferrari E., Ford J., Chiu S.K., Stam R.W., Kees U.R., Malinge S., Kotecha R.S.
Preclinical evaluation of carfilzomib for infant KMT2A-rearranged acute lymphoblastic leukemia.
Front. Oncol. 11:631594.1-631594.13(2021)

Cross-references
Encyclopedic resources Wikidata; Q54947221
Entry history
Entry creation15-May-2017
Last entry update10-Apr-2025
Version number8