ID   PER-785
AC   CVCL_IZ03
SY   PER-785A
DR   Wikidata; Q54947221
RX   PubMed=27443263;
RX   PubMed=33937032;
CC   Doubling time: 60 hours (PubMed=27443263).
CC   Omics: Transcriptomics; RNAseq.
CC   Miscellaneous: Sampling site from personal communication of Kotecha, Rishi S.
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
ST   Source(s): PubMed=27443263; PubMed=33937032
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 11,12
ST   D16S539: 9
ST   D21S11: 30,30.2
ST   D5S818: 11,12
ST   D7S820: 11,13
ST   TH01: 6,7
ST   TPOX: 8
ST   vWA: 14
DI   NCIt; C122617; Infant acute lymphoblastic leukemia with MLL rearrangement
DI   ORDO; Orphanet_513; Acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_IZ04 ! PER-785S
SX   Female
AG   2M
CA   Cancer cell line
DT   Created: 15-05-17; Last updated: 10-04-25; Version: 8
//
RX   PubMed=27443263; DOI=10.1038/leu.2016.165; PMCID=PMC5220136;
RA   Cruickshank M.N., Ford J., Cheung L.C., Heng J., Singh S., Wells J.,
RA   Failes T.W., Arndt G.M., Smithers N., Prinjha R.K., Anderson D.,
RA   Carter K.W., Gout A.M., Lassmann T., O'Reilly J., Cole C.H.,
RA   Kotecha R.S., Kees U.R.;
RT   "Systematic chemical and molecular profiling of MLL-rearranged infant
RT   acute lymphoblastic leukemia reveals efficacy of romidepsin.";
RL   Leukemia 31:40-50(2017).
//
RX   PubMed=33937032; DOI=10.3389/fonc.2021.631594; PMCID=PMC8082024;
RA   Cheung L.C., de Kraa R., Oommen J., Chua G.-A., Singh S., Hughes A.M.,
RA   Ferrari E., Ford J., Chiu S.K., Stam R.W., Kees U.R., Malinge S.,
RA   Kotecha R.S.;
RT   "Preclinical evaluation of carfilzomib for infant KMT2A-rearranged
RT   acute lymphoblastic leukemia.";
RL   Front. Oncol. 11:631594.1-631594.13(2021).
//