Cellosaurus logo
expasy logo

Cellosaurus ZR75T (CVCL_IW49)

[Text][XML][JSON]
Cell line name ZR75T
Accession CVCL_IW49
Resource Identification Initiative To cite this cell line use: ZR75T (RRID:CVCL_IW49)
Comments Part of: MD Anderson Cell Lines Project.
Population: Caucasian.
Omics: Proteomics; Expression; Reverse-phase protein array.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Glu162Lys (c.484G>A); ClinVar=VCV001034833; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Leu108Arg (c.323T>G); Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0588 (ZR-75-1)
Sex of cell Female
Age at sampling 63Y
Category Cancer cell line
Web pages Info; MCLP; -; https://tcpaportal.org/mclp/
Publications

PubMed=8430082; DOI=10.1073/pnas.90.3.1112; PMCID=PMC45821
Khandan Keyomarsi, Arthur Beck Pardee;
Redundant cyclin overexpression and gene amplification in breast cancer cells.
Proc. Natl. Acad. Sci. U.S.A. 90:1112-1116(1993)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, Agda Karina Eterovic, Lauren Averett Byers ...Show all 25 authors... , Michael A. Davies, Wan-Leng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_IW49
Encyclopedic resources Wikidata; Q54996136
Entry history
Entry creation03-Mar-2017
Last entry update10-Apr-2025
Version number12