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Cellosaurus FF452-3 (CVCL_IU56)

[Text version]
Cell line name FF452-3
Synonyms FF452 clone 3
Accession CVCL_IU56
Resource Identification Initiative To cite this cell line use: FF452-3 (RRID:CVCL_IU56)
Comments Population: African; Nigerian.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr163His (c.487T>C); ClinVar=VCV000376680; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Glu287Ter (c.859G>T); Zygosity=Unspecified (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2676 (P3HR-1)
Sex of cell Male
Age at sampling 7Y
Category Cancer cell line
Publications

PubMed=6276755; DOI=10.1038/295160a0
Heston L., Rabson M., Brown N., Miller G.
New Epstein-Barr virus variants from cellular subclones of P3J-HR-1 Burkitt lymphoma.
Nature 295:160-163(1982)

PubMed=6294333; DOI=10.1128/JVI.44.3.834-844.1982
Rabson M., Gradoville L., Heston L., Miller G.
Non-immortalizing P3J-HR-1 Epstein-Barr virus: a deletion mutant of its transforming parent, Jijoye.
J. Virol. 44:834-844(1982)

PubMed=6302703; DOI=10.1073/pnas.80.9.2762
Rabson M., Heston L., Miller G.
Identification of a rare Epstein-Barr virus variant that enhances early antigen expression in Raji cells.
Proc. Natl. Acad. Sci. U.S.A. 80:2762-2766(1983)

Cross-references
Cell line databases/resources cancercelllines; CVCL_IU56
Encyclopedic resources Wikidata; Q54834774
Entry history
Entry creation03-Mar-2017
Last entry update05-Oct-2023
Version number11