Cellosaurus cell line CL97-L2G (CVCL

Cellosaurus CL97-L2G (CVCL_IQ77)

Cross-references
Cell line name	CL97-L2G
Accession	CVCL_IQ77
Resource Identification Initiative	To cite this cell line use: CL97-L2G (RRID:CVCL_IQ77)
Comments	Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase. Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations	Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Gly719Ala (c.2156G>C); ClinVar=VCV000045225; Zygosity=Unspecified (PubMed=23024022). Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Thr790Met (c.2369C>T); ClinVar=VCV000016613; Zygosity=Unspecified (PubMed=23024022). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
Disease	Lung adenocarcinoma (NCIt: C3512)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_N826 (CL97)
Sex of cell	Male
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=23024022; DOI=10.1164/rccm.201207-1180OC Chi-Tai Yeh, Alexander T.H. Wu, Peter M.-H. Chang, Kuan-Yu Chen, Chia-Ning Yang, Shuenn-Chen Yang, Chao-Chi Ho, Chun-Chi Chen, Yu-Lun Kuo, Pei-Ying Lee, Yu-Wen Liu ...Show all 20 authors... , Chueh-Chuan Yen, Michael Hsiao, Pei-Jung Lu, Jin-Mei Lai, Liang-Shun Wang, Chih-Hsiung Wu, Jeng-Fong Chiou, Pan-Chyr Yang, Chi-Ying F. Huang; Show fewer authors Trifluoperazine, an antipsychotic agent, inhibits cancer stem cell growth and overcomes drug resistance of lung cancer. Am. J. Respir. Crit. Care Med. 186:1180-1188(2012)
Cell line databases/resources	cancercelllines; CVCL_IQ77
Encyclopedic resources	Wikidata; Q54813530
Entry history
Entry creation	03-Mar-2017
Last entry update	14-Aug-2025
Version number	16