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Cellosaurus PC/AA/C1/SB10 (CVCL_IQ06)

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Cell line name PC/AA/C1/SB10
Synonyms PC/AA/C1/SB/10; AA/C1/SB10
Accession CVCL_IQ06
Resource Identification Initiative To cite this cell line use: PC/AA/C1/SB10 (RRID:CVCL_IQ06)
Comments Selected for resistance to: ChEBI; CHEBI_64103; Sodium butyrate.
Transformant: ChEBI; CHEBI_21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Disease Colorectal adenoma (NCIt: C5673)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_IQ05 (PC/AA/C1/SB)
Sex of cell Male
Age at sampling 34Y
Category Cancer cell line
Publications

DOI=10.1007/978-1-4612-0411-4_28
Ann C. Williams, Anna M. Manning, Sara J. Harper, Christos Paraskeva;
Multiple steps in the in vitro immortalisation and neoplastic conversion of human colonic epithelial cells.
(In book chapter) Neoplastic transformation in human cell system. Mechanism of carcinogenesis; Rhim, Johng Sik & Dritschilo, Anatoly (eds.); pp.281-290; Humana Press; New York; USA (1990)

PubMed=2369746
Ann C. Williams, Sara Jayne Harper, Christos Paraskeva;
Neoplastic transformation of a human colonic epithelial cell line: in vitro evidence for the adenoma to carcinoma sequence.
Cancer Res. 50:4724-4730(1990)

PubMed=16465285; DOI=10.1038/sj.cdd.4400293
Alison Joy Butt, Angela Hague, Christos Paraskeva;
Butyrate- but not TGFbeta1-induced apoptosis of colorectal adenoma cells is associated with increased expression of the differentiation markers E-cadherin and alkaline phosphatase.
Cell Death Differ. 4:725-732(1997)

Cross-references
Encyclopedic resources Wikidata; Q54938516
Polymorphism and mutation databases IARC_TP53; 23789
Entry history
Entry creation03-Mar-2017
Last entry update19-Dec-2024
Version number7