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Cellosaurus PC/AA/C1/SB10 (CVCL_IQ06)

[Text version]
Cell line name PC/AA/C1/SB10
Synonyms PC/AA/C1/SB/10; AA/C1/SB10
Accession CVCL_IQ06
Resource Identification Initiative To cite this cell line use: PC/AA/C1/SB10 (RRID:CVCL_IQ06)
Comments Selected for resistance to: ChEBI; CHEBI_64103; Sodium butyrate.
Transformant: ChEBI; CHEBI_21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Disease Colorectal adenoma (NCIt: C5673)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_IQ05 (PC/AA/C1/SB)
Sex of cell Male
Age at sampling 34Y
Category Cancer cell line
Publications

DOI=10.1007/978-1-4612-0411-4_28
Williams A.C., Manning A., Harper S.J., Paraskeva C.
Multiple steps in the in vitro immortalisation and neoplastic conversion of human colonic epithelial cells.
(In book chapter) Neoplastic transformation in human cell system. Mechanism of carcinogenesis; Rhim J.S., Dritschilo A. (eds.); pp.281-290; Humana Press; New York; USA (1990)

PubMed=2369746
Williams A.C., Harper S.J., Paraskeva C.
Neoplastic transformation of a human colonic epithelial cell line: in vitro evidence for the adenoma to carcinoma sequence.
Cancer Res. 50:4724-4730(1990)

PubMed=16465285; DOI=10.1038/sj.cdd.4400293
Butt A.J., Hague A., Paraskeva C.
Butyrate- but not TGFbeta1-induced apoptosis of colorectal adenoma cells is associated with increased expression of the differentiation markers E-cadherin and alkaline phosphatase.
Cell Death Differ. 4:725-732(1997)

Cross-references
Encyclopedic resources Wikidata; Q54938516
Polymorphism and mutation databases IARC_TP53; 23789
Entry history
Entry creation03-Mar-2017
Last entry update19-Dec-2024
Version number7